Center for Human Toxicology
CHT Directors:
Co-Directors,
Dennis Crouch, BS, MBA
Diana Wilkins, Ph.D.
Associate Directors,
Douglas Rollins, MD, Ph.D.
Rodger Foltz, Ph.D.
David Moody, Ph.D.
Assistant Directors,
David Andrenyak, Ph.D., DABFT
Matthew Slawson, Ph.D.
Staff:
David Adrenyak
Ph.D., DABFT. Dr. Andrenyak has been employed
as a toxicologist at the Center for Human Toxicology since 1988 and is
currently an Assistant Director. He is involved in analyzing drugs and
poisons in samples submitted to the Center for the various contracts. David
also coordinates the analysis of forensic consultant case samples.
Tim Bolduc
Mr. Bolduc is a doctoral canidate in the Department of Pharmacology and Toxicology. He is performing his thesis research with Dr. Wilkins investigating the mechanism of action of several nutritional supplements. His previous work includes the development of an LC-MS method for the detection of salvinorin A.
Chad Borges
Ph.D. Dr. Borges was a graduate student at the Center for Human Toxicology. After a two year postdoc at Michigan State University where he recieved training on the analysis of biological macromolecules by mass spectrometry, he joined the newly-formed Sports Medicine Research and Testing Laboratory as a Research Assistant Professor. His interests lie in analytical biochemistry.
Amy B. Cadwallader
Ms. Cadwallader is a doctoral canidate in the Department to Pharmacology and Toxicology under the direction of Dr. Douglas Rollins. The goals of her thesis research are to determine the cellular mechanisms of action of anabolic steroids and establish a structure-activity relationship between anabolic steroids and their subsequent anabolic activity. Her previous work involved developing an analytical LC-MS method for the detection of THG in urine.
Yan Chang
Ph.D., Dr. Chang is working as a senior laboratory scientist in the Center for Human Toxicology under the direction of Dr. David Moody. Currently her research work focuses on the in-vitro metabolism of buprenorphine in human liver microsomes.
Meng Chen
Meng has a Masters degree in Medical Technology
from the University of Utah. He has been working at CHT since August
2000 as a Laboratory Specialist. Currently, he is working on projects dealing
with the analysis of the drugs of abuse and methods development.
Dennis J. Crouch
B.S., M.B.A. Mr. Crouch has been employed
at the Center for Human Toxicology since 1977. He currently serves
as one of the Co-Directors of the Center and has an appointment in Pharmacology
and Toxicology as a Research Associate Professor. Mr. Crouch has long
standing interests in analytical toxicology, forensic toxicology and drugs
in transportation and workplace safety. His current research projects include
assessing the utility of saliva and liquid perspiration as drug testing
specimens, evaluating on-site drug testing devices for use in workplace
and transportation testing and safety programs, and, the analysis of performance-enhancing drugs in sport.
Jonathan Danaceau
Ph.D. Dr. Danaceau has been employed as an associate toxicologist at the Center since 2002. He has a Ph.D. in neuroscience and extensive experience in analytical methods including GC/MS, LC/MS, and HPLC. His interests include the analysis of monoamine neurotransmitters and drugs of abuse by mass spectrometry and HPLC. He is also involved in a project to investigate the development of tolerance to methamphetamine induced neurotoxicity. Other interests include investigating biochemical markers for autism and the analysis of drugs of abuse in saliva.
Jayme Day
Ms. Day is comleting a Bachelors
of Science degree from the University of Utah. She is a lab assistant and has
been working at the Center for the past four years. She is currently working on a clinical study of fentanyl for use in pediatric indications, and hair testing methods.
Wendy Fang
Ph.D. in analytical chemistry. Wendy joined the Center for Human Toxicology in July, 2002 and is currently an assistant toxicologist. She is involved in quantitative analysis of drugs and their metabolites in biological samples and analytical method development and validation.
Rodger L. Foltz
Ph.D. Research Professor in the Department of
Pharmacology and Toxicology and an Associate Director at the Center for
Human Toxicology. He has co-authored more than 100 publications concerning
the determination of drugs and metabolites in physiological specimens by
chromatographic and mass spectrometric methods.
Lolita L. Lamm
Ms. Lamm has a A.S. in environmental technology, B.S. in chemistry, and is a laboratory technician at the center. She performs extractions of drugs of abuse from biological specimens by SPE, RIA, and other specialized tests.
Shen-Nan Lin
Ph.D. Dr. Lin is a Research Associate Professor
in the Department of Pharmacology and Toxicology. He has been with the
Center since March of 1998 as a Research Toxicologist. Shen-Nan participates in the Medication Drug Development
contracts as a senior analyst and in collaborative research programs with
other faculty. He has made major contributions to the design and implementation
of the state of the art bio analytical mass spectrometric methods.
Nicole Miller
BS in Biology from the University of Utah. Nicole works as a laboratory specialist in the Sports Medicine and Research Testing Laboratory. She is working with other members of the SMRT staff to develop, validate, and perform ongoing drug tests to prevent the abuse of performance-enhancing drugs in competition sports.
Kim M. Monti
B.S. in Chemistry and Biology. Ms. Monti is an
Associate Toxicologist, and the quality Control/Quality Assurance Manager.
She has sixteen years of experience in mass spectrometry and toxicology and has been
at the Center for fourteen years. As QC/QA manager, prepares, reviews and
certifies quality control materials for the analytical procedures; maintains
quality control records and personnel training records; audits reports
to insure accuracy; assures compliance with relevant federal, state and/or
private regulations and Good Laboratory Practice (GLP) protocol. Ms. Monti is also a member of the Society of Quality Assurance.
David E. Moody
Ph.D. Dr. Moody is an Associate Director at the
Center and a Research Associate Professor in the Department of Pharmacology
and Toxicology. Dr. Moody has been been on the Center staff since 1986.
His current research interests include development of mass spectrometric
methods and the evaluation of immunoassay methods for detection of abused
drugs and anti-abuse medications, and the role of specific human cytochrome
P450s in the metabolism of drugs.
Dixie Peeler
B.S. in Biology. Dixie has been with the center for over a year. She is currently coordinating clinical reasearch in Human steroid profiles. She also performs extracations of steroids and their metabolites from Biological samples.
Cristian Peme
Mr. Peme is completing a bachelors of science in the medical laboratory science program. Employed since 2003, he is currently working on tolerance studies in relation to methamphetamine neurotoxicity, and analysis of monoamines by HPLC.
Douglas E. Rollins
M.D., Ph.D. Associate Director of the Center
for Human Toxicology and Professor of Pharmacology and Toxicology. Dr.
Rollins was Director of the Center for Human Toxicology from 1983 - 1999.
He was also Medical Director of the Utah Poison Control Center. His research
interests include the measurement of drugs and their metabolites in human
hair and clinical pharmacology and toxicology.
Matt Slawson
Ph.D. Dr. Slawson has been employed
at Center since 1991, beginning as a lab assistant, then a graduate student,
a post-doc and is currently a Research Assistant Professor and Assistant Director. Since 1991, Dr. Slawson has been engaged in research of the activity
of Phase I and Phase II drug metabolizing enzymes, as well as using GC-MS/MS
to identify previously unreported metabolites of LSD.
Dr. Slawson is currently involved in developing and validating sensitive and specific
methods for the detection of drugs using HPLC coupled with mass spectrometry
(both MS and MS/MS). He is also working on GLP grade methods validations, quantitating
trace amounts of drugs in hair, and any consulting case or project that
may be amenable to analysis by HPLC-MS or HPLC-MS/MS.
Stacy Smeal
Miss Smeal is a graduate student in the Department
of Pharmacology and Toxicology. She is performing thesis research entitled, "Mechanism of Cannabinoid Incorporation in Hair." Her previous work includes studies on selective decontamination procedures and their ability to remove environmental contamination of hair by drugs of abuse.
Bobbie Smith
Ms. Smith is an Administrative Assistant and has
been working at the Center since 1992. She keeps track of budgets,
does payroll for the Center employees, maintains daily operations in the
front office and assists in grant and contract preparation.
Diana G. Wilkins
Ph.D. Research Associate Professor in the Department
of Pharmacology and Toxicology, and Co-Director of the Center
for Human Toxicology. Dr. Wilkins research interests include investigation
of the disposition of drugs of abuse in biological matrices, mechanisms
of methamphetamine tolerance, and applications of mass spectrometry in
biomedical research. She also participates in teaching undergraduate and
graduate courses in clinical and analytical toxicology, pharmacology and
statistics for pharmacological research.
