A.  Positions and Honors

Positions and Employment
1983-1999      Staff Research Biologist - Scripps Institution of Oceanography, UC San Diego
1999               Instructional Research Staff, Dept. of Medicinal Chemistry, University of Utah

B.  Peer-reviewed publications (in chronological order).

1. Tasdemir, D.; Marshall, K.M.; Concepcion, G.P.; Mangalindan, G.C.; Harper, M.K.; Barrows, L.R.; Ireland, C.M. Deoxyamphimedine, A New Pryridoacridine Alkaloid from Two Tropical Xestospongia sponges  J. Org. Chem.  2001, 66, 3246-48.
   
   
2. Tasdemir, D.; Mangalindan, G.C.; Concepcion, G.P.; Harper, M.K.; Ireland, C.M.  3,7-Dimethylguanine, A New Purine from a Philippine Sponge Zyzzya fuliginosa Chem. Pharm. Bull. 2000, 29, 1628-30.
   
   
3. Tasdemir, D.; Concepcion, G.P.; Mangalindan, G.C.; Harper, M.K.; Hajdu, E.; Ireland, C.M.  Corrigendum to “New Terpenoids from a Cacospongia sp. from the Philippines Tetrahedron (2000) 56, 9025-30" Tetrahedron 2001, 57, 5681.
   
   
4. Qureshi, A.; Salva, J.; Harper, M.K.; Faulkner, D.J.  New cyclic peroxides from the Philippine sponge Plakinastrella sp. J. Nat. Prod.; (Addition/Correction) 2001, 61, 553.
   
   
5. Tasdemir, D.;  Mangalindan, G.C.; Concepción, G.P.; Verbitski, S.M.; Rabindran, S.; Miranda, M.;  Greenstein, M.; Hooper, J.N.A.; Harper, M.K.; Ireland, C.M. Bioactive Isomalabaricane Triterpenes from the Marine Sponge Rhabdastrella globostellata J. Nat. Prod. 2002, 65, 210-14.
   
   
6. Tasdemir, D.;  Mallon, R.; Greenstein, M.; Feldberg, L.R.; Kim, S.C.; Collins, K.;  Wojciechowicz,W.; Mangalindan, G.C.; Concepción, G.P.; Harper, M.K.; Ireland, C.M. Aldisine Alkaloids from the Philippine Sponge Stylissa massa are Potent Inhibitors of Mitogen-Activated Protein Kinase Kinase-1 (MEK-1) J. Med. Chem. 2002, 45, 529-32.
   
   
7. Bugni, T.S.; Concepcion, G.P.; Mangalindan, G.C.; Harper, M.K.; James, R.D.; Ireland, C.M. p-Sulfooxyphenylpyruvic acid from the red macro alga Ceratodictyon spongiosum and its sponge symbiont Haliclona cymaeformis Phytochemistry 2002, 60, 361-363.
   
   
8. Tasdemir, D.; Bugni, T.S.; Mangalindan, G.C.; Concepción, G.P.; Harper, M.K.; Ireland, C.M. Cytotoxic Bromoindole Derivatives and Terpenes from the Philippine Marine Sponge Smenospongia sp. Z. Naturforsch, 2002, 57C, 914-922.
   
   
9. Tasdemir, D.; Bugni, T.S.; Mangalindan, G.C.; Concepción, G.P.; Harper, M.K.; Ireland, C.M. Bisaboline Type Sesquiterpenes from a Marine Didiscus Sponge Turk. J. Chem. 2002, 26, 1-7.
   
   
10. Chevallier, C.; Richardson, A.D.; Edler, M.C.; Hamel. E.; Harper, M.K.; Ireland, C.M. A New Cytotoxic and Tubulin-interactive Milnamide Derivative from a Marine Sponge Cymbastela sp. Org Lett. (2003) 5, 3737-3739.
    
    
11. Sandoval, I.T.; Davis, R.A.; Bugni, T.S.; Concepcion, G.P.; Harper, M.K.; Ireland, C.M. Cytotoxic Isoquinoline quinones from sponges of the genus Petrosia Nat. Prod. Res. (2003) 18, 89-93.
    
    
12. Lerch, M.L.; Harper, M.K.; Faulkner, D.J. Brominated polyacetylenes from the Philippines sponge Diplastrella sp. J. Nat. Prod. (2003) 5, 667-670.
    
    
13. Ireland, C.M.; Aalbersberg, W.; Andersen, R.J.; Ayral-Kaloustian, S.; Berlinck, R.; Bernan, V.S.;  Carter, G.T.; Churchill, A.C.L.; Clardy, J.; Concepcion, G.P.; De Silva, E.D.; Discafani, C.; Fojo, T.; Frost, P.; Gibson, D.; Greenberger, L.M.; Greenstein, M.; Harper, M.K.; Mallon, R. ; Loganzo, F.; Nunes, M.; Poruchynsky, M.S.; Zask, A.  Anticancer Agents from Unique Natural Products Sources Pharm. Bio. (2003) 41, Supplement, 15-38.
    
    
14. Davis, R.A.; Mangalindan, G.C.; Bojo, Z.P.; Antemano, R.R.; Rodriguez, N.O.; Concepcion, G.P.; Samson, S.C.; de Guzman, D.; Cruz, L.J.; Tasdemir, D.; Harper, M.K.; Feng, X.; Carter, G.T.; Ireland, C.M.  Microcionamides A and B, Bioactive Peptides from the Philippine Sponge Clathria (Thalysias) abietina  J. Org.Chem. (2004) 69, 4170-4176.
    
    
15. Bugni, T.S.;  Singh, M.P.; Chen, L.;  Arias, D.A.; Harper, M.K.; Greenstein, M.; Maiese,M.M.; Concepcion, G.P.; Mangalindan, G.C.; Ireland, C.M. Kalihinols from two Acanthella cavernosa sponges: inhibitors of bacterial folate biosynthesis Tetrahedron (2004) 60, 6981-6988.
    
    
16. Bobzin, S.C.; Cardellina, J.H. 2nd; Gerwick, W.H.; Okuda, R.K.; Harper, M.K.; Ireland, C.M. Special issue in honor of D. John Faulkner and Paul J. Scheuer J. Nat. Prod. (2004) 67, 1201-1203.
    
    
17. Ratnayake, A.S; Davis, R.A.; Harper, M.K.; Veltri, C.A.; Andjelic, C.D.; Barrows, L.R.; Ireland, C.M. Aurantosides G, H, and I: three new tetramic acid glycosides from a Papua New Guinea Theonella swinhoei. J. Nat. Prod. (2005) 68, 104-107.
    
    
18. Ridley, C.P.; Bergquist, P.R.; Harper, M.K.; Faulkner, D.; Hooper, J.N.A.; Haygood, M.G.         Speciation and biosynthetic variation in four dictyoceratid sponges and their cyanobacterial symbiont, Oscillatoria spongeliae Chem. Biol. (2005) 12, 397-406.

C.  Research Support

None