Publications: Patents

Patents and Patent Applications

• G.D. Prestwich, L. Feng, and H. Wojtasek, "Materials and Methods Useful to Affect Apoptosis," U.S. Provisional Application No. 60/151,032 filed August 27, 1999, PCTFiling WO 01/15722 A2, March 8, 2001.

• J.S. Brugge, G.D. Prestwich, and V.R. Rao, "Library Screening with Biotinylated Phosphoinositide Polyphosphate Probes", U.S. Patent Application in preparation.

• J.-w. Kuo, D.A. Swann, and G.D. Prestwich, "Water-Insoluble Derivatives of Hyaluronic Acidand Their Methods of Preparation and Use," U.S.Patent No.6,013,679 (January11, 2000).

• J.-w. Kuo, D.A. Swann, and G.D. Prestwich, "Method for Treating Wounds Using Modified Hyaluronic Acid Crosslinked with Biscarbodiimide", U.S. Patent No. 6,096,727 (August1,2000).

• G.D. Prestwich, Y. Luo, and K.R. Kirker, "Hydrogel Films and Methods of Making and Use Thereof", U.S.Provisional Application No. 60/218,725, Filed July 17, 2000; PCT Filing WO 02/06373 A1, January 24, 2002.

• W.G. Pitt and G.D. Prestwich, "Attachment of Polysaccharides to Metallic Surfaces",U.S.Provisional Application, Filed April 23, 2001.

• Y. Luo, G.D. Prestwich, J. Kopecek, and Z.-R. Lu, "Hyaluronic Acid Containing Bioconjugates: Targeted Delivery of Anti-Cancer Drugs to Cancer Cells", U.S.Provisional Application, U.S. Ser. No. 60/289,038, Filed May 2, 2001.

• G.D. Prestwich, "Didehydrogeranylgeranyl (ￇG) and Related Materials and Methods", U.S. Provisional Patent Application, Filed June 7, 2001.

• G.D. Prestwich, "Compositions and Methods of Use of Derivatives of Phosphatidylethanolamine-Extended Phosphatidylinositol 4,5-Bisphosphate (Pea-PIP2)", U.S. Provisional Patent Application, Filed March 28, 2002; PCT filed March 26, 2003.

• L. Zhang and G.D. Prestwich, "Preblocking with non-HA GAGs Increases Effectiveness of HA Conjugated Anticancer Agents", U.S. Provisional Patent Application, Filed May 4, 2001; PCT filed May 6, 2002; Utility patent filed May 6, 2003.

• G.D. Prestwich, P.W. Rzepecki, C.G. Ferguson, P.O. Neilsen, A.M. Branch, and L.R.Crosby, "Hybrid Phosphoinositide Phospholipids Compositions and Use", U.S. Provisional Patent Application, Filed June 28, 2002.

• C.G. Ferguson and G.D. Prestwich, "Lipid Overlay Systems for Detecting Lipid Recognition Proteins and Methods of Use", U.S. Provisional Patent Application filed.

• B.E. Drees, P.O. Neilsen, and G.D. Prestwich, "Lipid Phosphatase Assays in Disease Detection and Drug Delivery", U.S. Provisional Patent Application filed.

• L. Feng and G.D. Prestwich, "Dye-Glutathione Conjugate as Universal Detector of GST-Fusion Proteins", U.S. Provisional Patent Application filed.

• G.D. Prestwich, Y. Xu, and L. Qian, "Analogs of Lysophosphatidic Acid and Methods of Making and Use Thereof", U.S. Provisional Patent Application filed April 9, 2003; PCT/US2004/11060 filed April 9, 2004 (WO 2004/09288 A2, October 28, 2004).

• G.D. Prestwich, X.Z. Shu, Y. Luo, and Y. Liu,"Crosslinked Compounds and Methods of Making and Using Thereof", U.S. Provisional Patent Application filed May 7, 2003.

• G.D. Prestwich, S.D. Gray, and J. Shelby, "Anti-adhesion Composites and Methods of Use Thereof", U.S. Provisional Patent Application filed May 7, 2003.

• Y. Luo and G.D. Prestwich, "Photocrosslinkers and Methods of Use Thereof", U.S.Provisional Patent Application filed May 30, 2003.

• J.-w. Kuo, D.A. Swann, and G.D. Prestwich, "Water-Insoluble Derivatives of Hyaluronic Acid Crosslinked with a Biscarbodiimide", U.S.Patent No. 6,537,979 (March 25, 2003).

• X.Z. Shu, Y. Liu, and G.D. Prestwich, "Modified Macromolecules and Methods of Making and Using Thereof", U.S. Provisional Patent Application Serial No. 60526797, filed December 4, 2003. Free Utillity and PCT filed December 5, 2004.

• C.G. Ferguson and G.D. Prestwich,"Compounds and Methods of Use Thereof for Assaying Lysophospholipase D Activity", PCT Filing WO 2004/053459 A2, June 24, 2004.

• B.E. Drees, L. Chakravarty, G.D. Prestwich, G. Dormﾬ M. Kavecz, A. Lukacs, L.Urge, F. Darvas, P. Rzepecki, and C.G. Ferguson, "Compounds Having Inhibitory Activity Towards Phosphatidylinositol 3-Kinase and Methods of Use Thereof", PCT/US2004/018753, filed October 13, 2004.