Jindrich (Henry) Kopecek

Abstracts Patents


A. ARTICLES

Revised October 2011

394.

S. Low, J. Kopecek
Targeting Polymer Therapeutics to Bone
Adv, Drug Delivery Rev., submitted

393.

K. Fowers, J. Kopecek
Targeting of Multidrug Resistant Human Ovarian Carcinoma Cells with Anti-P-Glycoprotein Antibody Conjugates
Macromol. Biosci., submitted

392.

J. Liu, P. Kopeckova, H. Pan, M. Sima, P. Buhler, P. Wolf, U. Elsasser-Beile, J. Kopecek
Prostate Cancer Targeted N-(2-Hydroxypropyl)methacrylamide (HPMA) Copolymer-Docetaxel Conjugates
Macromol. Biosci., submitted

391.

K. Wu, J. Yang, J. Liu, J. Kopecek
Coiled-Coil Based Drug-Free Macromolecular Therapeutics: In Vivo Efficacy
J. Controlled Release, doi:10.1016/j.jconrel.2011.08.002 (2011)

390.

L. Wu, J. Yang, J. Kopecek
Hybrid Hydrogels Self-Assembled from Graft Copolymers Containing Complementary beta-Sheets as Hydroxyapatite Nucleation Scaffolds
Biomaterials, 32, 5341-5353 (2011)

389.

E. Segal, H. Pan, L. Benayoun, P. Kopeckova, Y. Shaked, J. Kopecek, R. Satchi-Fainaro
Enhanced Safety Profile and Antitumor Activity of Targeted HPMA Copolymer-Alendronate-TNP470 Nanoconjugate in the Treatment of Bone Malignancies
Biomaterials, 32, 4450-4463 (2011)

388.

S. Krimmer, H. Pan, J. Liu, J. Yang, J. Kopecek
Synthesis and Characterization of Poly(e-caprolactone)-block-Poly[N-(2-Hydroxypropyl)methacrylamide] Micelles for Drug Delivery
Macromolecular Biosci., in press

387.

K. Luo, J. Yang, P. Kopeckova, J. Kopecek
Biodegradable Multiblock N-(2-Hydroxypropyl)methacrylamide Copolymers via Reversible Addition-Fragmentation Chain Transfer Polymerization and Click Chemistry
Macromolecules, 44, 2481-2488 (2011)

386.

H. Pan, J. Yang, P. Kopeckova, J. Kopecek
Backbone Degradable Multiblock HPMA Copolymer Conjugates via RAFT Polymerization and Thiol-ene Coupling Reaction
Biomacromolecules 12, 247-252 (2011)

385.

J. Yang, K. Luo, H. Pan, P. Kopeckova, J. Kopecek
Synthesis of Biodegradable Multiblock Copolymers by Click Coupling of RAFT-Generated Heterotelechelic PolyHPMA Conjugates
Reactive Functional Polym., 71, 294-302 (2011)

384.

K.M. Giantsos-Adams, V. Lopez-Quintaro, P. Kopeckova, J. Kopecek, J.M. Tarbell, R. Dull
Study of the Therapeutic Benefit of Cationic Copolymer Administration to Vascular Endothelium Under Mechanical Stress
Biomaterials 32, 288-294 (2011)

383.

J. Kopecek, P. Kopeckova
Design of Polymer-Drug Conjugates
In: Drug Delivery in Oncology, F. Kratz, P. Senter, H. Steinhagen, Eds., Wiley-VCH, Weinheim, Germany, in press

382

J. Kopecek
Biomaterials and Drug Delivery - Past, Present, and Future
Molecular Pharmaceutics 7, 922-925 (2010)

381.

J. Liu, H. Bauer, J. Callahan, P. Kopeckova, H. Pan, J. Kopecek
Endocytic uptake of a large array of HPMA copolymers: Elucidation into the dependence on the physicochemical characteristics
J. Controlled Release 143, 71-79 (2010)

380.

J. Kopecek, P. Kopeckova
HPMA Copolymers: Origins, Early Developments, Present, and Future
Adv. Drug Delivery Rev., 62, 122-149 (2010)

379.

K. Wu, J. Liu, R.N. Johnson, J. Yang, J. Kopecek
Drug-Free Macromolecular Therapeutics: Induction of Apoptosis by Coiled-Coil Mediated Crosslinking of Antigens on Cell Surface
Angew. Chem. Int. Ed. 49, 1451-1455 (2010)

378.

J. Yang, M.T. Jacobsen, H. Pan, J. Kopecek
Synthesis and Characterization of Enzymatically Degradable PEG-Based Peptide-Containing Hydrogels
Macromol. Biosci. 10, 445-454 (2010)

377.

J. Kopecek
Hydrogels. From Soft Contact Lenses and Implants to Self-Assembled Nanomaterials
J. Polym. Sci: Part A: Polym. Chem., 47,5929-5946 (2009)

376.

L.C. Radu-Wu, J. Yang, K. Wu, J. Kopecek
Self-Assembled Hydrogels from Poly[N-(2-Hydroxypropyl)methacrylamide] Grafted with beta-Sheet Peptides
Biomacromolecules 10, 2319-2327 (2009)

375.

R. Sheparovych, Y. Roiter, J. Yang, J. Kopecek, S. Minko
Stimuli-Responsive Properties of Peptide-Based Copolymers Studied via Directional Growth of Self-Assembled Patterns on Solid Substrate
Biomacromolecules 10, 1955-1961 (2009)

374.

J. Liu, P. Kopeckova, P. Buhler, P. Wolf, H. Pan, H. Bauer, U. Elsasser-Beile, J. Kopecek
Biorecognition and Subcellular Trafficking of HPMA Copolymer-Anti-PMSA Antibody Conjugates by Prostate Cancer Cells
Molecular Pharmaceutics, 6, 959-970 (2009)

373.

J. Callahan, P. Kopeckova, J. Kopecek
The Intracellular Trafficking and Subcellular Distribution of a Large Array of HPMA Copolymers
Biomacromolecules, 10, 1704-1714 (2009)

372.

S. Gao, Y. Sun, P. Kopeckova, C.M. Peterson, J. Kopecek
Antitumor Efficacy of Colon-Specific HPMA Copolymer-9-Aminocamptothecin Conjugate in Mice Bearing Human Colon Carcinoma Xenografts
Macromolecular Bioscience, 9, 1135-1142 (2009)

371.

E. Segal, H. Pan, P. Ofek, T. Ugadawa, P. Kopeckova, J. Kopecek, R. Satchi-Fainaro
Targeting-Angiogenesis-Dependent Calcified Neoplasms Using Combined Polymer Therapeutics
PLoS ONE, 4(4) e5233 (2009); doi:10.1371/journal.pone.0005233

370. R. Johnson, P. Kopeckova, J. Kopecek
Synthesis and Evaluation of Multivalent Branched HPMA copolymer-Fab' conjugates targeted to the B-cells antigen CD20
Bioconjugate Chemistry, 20, 129-137 (2009)
369.

J. Kopecek, J. Yang
Peptide-Directed Self-Assembly of Hydrogels
Acta Biomaterialia, 5, 805-816 (2009)

368.

L.C. Radu, J. Yang, J. Kopecek
Self-Assembling Block Copolymers of Poly[N-(2-hydroxypropyl)methacrylamide] and a Beta-Sheet Peptide
Macromol. Biosci., 9, 36-44 (2009)

367.

K. Dusek, M. Duskova-Smrckova, J. Yang, J. Kopecek
Coiled-Coil Hydrogels. Chain-Ring Competition and Association-Dissociation Equilibria
Macromolecules, 42, 2265-2274 (2009)

366.

W. Yuan, J. Yang, P. Kopeckova, J. Kopecek
Smart Hydrogels Containing Adenylate Kinase: Translating Substrate Recognition into Macroscopic Motion,
J. Am. Chem. Soc. 130, 15760-15761 (2008)

365. S.C. Miller, H. Pan, D. Wang, B.M. Bowman, P. Kopeckova, J. Kopecek
Feasibility of Using a Bone-Targeted, Macromolecular Delivery System Coupled with Prostaglandin E1 to Promote Bone Formation in Aged, Estrogen-Deficient Rats Pharmaceutical Res., 25, 2889-2895 (2008)
364.

J. Hongrapipat, P. Kopeckova, J. Liu, S. Prakongpan, J. Kopecek
Combination Chemotherapy and Photodynamic Therapy with Fab' Fragment Targeted HPMA Copolymer Conjugates in Human Ovarian Carcinoma Cells
Molecular Pharmaceutics, 5, 696-709 (2008)

363.

V. Cuchelkar, P. Kopeckova, J. Kopecek
Novel HPMA Copolymer-Bound Constructs for Combined Tumor and Mitochondrial Targeting
Molecular Pharmaceutics, 5, 76-786 (2008)

362.

H. Pan, M. Sima, P. Kopeckova, K. Wu, S. Gao, J. Liu, D. Wang, S.C. Miller, J. Kopecek
Biodistribution and Pharmacokinetic Studies of Bone-Targeting N-(2-Hydroxypropyl)methacrylamide Copolymer-Alendronate Conjugates
Molecular Pharmaceutics, 4, 548-558 (2008)

361.

H. Pan, J. Liu, Y. Dong, M. Sima, P. Kopeckova, M.L. Brandi, J. Kopecek
Release of Prostaglandin E1 from N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates by Bone Cells
Macromol. Biosci., 8, 599-605 (2008)

360.

V. Cuchelkar, P. Kopeckova, J. Kopecek
Synthesis and Biological Evaluation of Disulfide-Linked HPMA Copolymer- Mesochlorin e6 Conjugates
Macromol. Biosci., 8, 375-383 (2008)

359.

K. Wu, J. Yang, C. Konak, P. Kopeckova, J. Kopecek
Novel Synthesis of HPMA Copolymers Containing Peptide Grafts and their Self-Assembly into Hybrid Hydrogels
Macromol. Chem. Phys., 209, 467-475 (2008)

358.

J. Yang, K. Wu, C. Konak, J. Kopecek
Dynamic Light Scattering Study of the Self-Assembly of HPMA Hybrid Graft Copolymers
Biomacromolecules, 9, 510-517 (2008)

357.

S.-Q. Gao, Y. Sun, P. Kopeckova, C.M. Peterson, J. Kopecek
Pharmacokinetic Modeling of Absorption Behavior of 9-Aminocamptothecin (9-AC) Released from Colon-specific HPMA Copolymer-9-AC Conjugate in Rats
Pharmaceutical Res., 25, 218-226 (2008)

356.

J. Hongrapipat, P. Kopeckova, S. Prakongpan, J. Kopecek
Enhanced Antitumor Activity of Combinations of Free and HPMA Copolymer-bound Drugs
Int. J. Pharmaceutics, 351, 259-270 (2008)

355.

H. Pan, J. Kopecek
Multifunctional Water-Soluble Polymers for Drug Delivery
In: Multifunctional Pharmaceutical Nanocarriers, V.P. Torchilin, Ed., Springer, New York, 2008, pp. 81-142.

354.

C. Xu, J. Kopecek
Genetically Engineered Block Copolymers: Influence of the Length and Structure of the Coiled-Coil Block on Hydrogel Self-Assembly
Pharmaceutical Res., 25, 674-682 (2008)

353.

H. Pan, P. Kopeckova, J. Liu, D. Wang, S.C. Miller, J. Kopecek
Stability in Plasmas of Various Species of HPMA Copolymer-PGE1 Conjugates
Pharmaceutical Res., 24, 2270-2280 (2007)

352.

J. Kopecek
Hydrogel Biomaterials: A Smart Future?
Biomaterials, 28, 5185-5192 (2007)

351.

D. Wang, S.C. Miller, L.S. Shlyakhtenko, A.M. Portillo, X.-M. Liu, K. Papangkorn, P. Kopeckova, Y. Lyubchenko, W.I. Higuchi, J. Kopecek
Osteotropic Peptide That Differentiates Functional Domains of the Skeleton
Bioconjugate Chem., 18, 1375-1378 (2007)

350.

A. Malugin, P. Kopeckova, J. Kopecek
Liberalization of Doxorubicin from HPMA Copolymer Conjugate is Essential for the Induction of Cell Cycle Arrest and Nuclear Fragmentation in Ovarian Carcinoma Cells
J. Contr. Rel., 124, 6-10 (2007)

349. H. Ding, P. Kopeckova, J. Kopecek
Self-Association Properties of HPMA Copolymers Containing an Amphipatic Heptapeptide
J. Drug Targeting, 15, 465-474 (2007)
348. J. Kopecek
Polymeric Biomaterials and Drug Delivery Systems
J. Jpn. Biomat. Soc., 25, 123-135 (2007)
347. J. Kopecek. J. Yang
Hydrogels as Smart Biomaterials
Polymer Int., 56, 1078-1098 (2007)
346. S. Gao, Z.-R. Lu, P. Kopeckova, J. Kopecek
Biodistribution and Pharmacokinetics of Colon-Specific HPMA Copolymer-9-Aminocamptothecin Conjugate in Mice
J. Contr. Rel., 117, 179-185 (2007)
345. C. Xu, J. Kopecek
Self-Assembling Hydrogels
Polymer Bulletin, 58, 53-63 (2007)
344. M. Oman, J. Liu, J. Chen, D. Durrant, H.-S. Yang, Y. He, P. Kopeckova, J. Kopecek, R.M. Lee
Using N-(2-Hydroxypropyl)methacrylamide Copolymer Drug Bioconjugate as a Novel Approach to Deliver a Bcl-2-Targeting Compound HA14-1 In Vivo
Gene Ther. Mol. Biol. 10, 113-122 (2006)
343. D. Wang, M. Sima, R.L. Mosley, J.P. Davda, N. Tietze, S.C. Miller, P.R. Gwilt, P. Kopeckova, J. Kopecek
Pharmacokinetic and Biodistribution Studies of a Bone-targeting Drug Delivery System Based on N-(2-Hydroxypropyl)methacrylamide (HPMA) Copolymers
Molecular Pharmaceutics, 3, 717-725 (2006)
342. H. Ding, W.M. Prodinger, J. Kopecek
Two-Step Fluorescence Screening of CD21-Binding Peptides with One-Bead One-Compound Library and Investigation of Binding Properties of HPMA Copolymer-Peptide Conjugates
Biomacromolecules, 7, 3037-3046 (2006)
341. J. Callahan, J. Kopecek
Semitelechelic HPMA Copolymers Functionalized with Triphenylphosphonium as Drug Carriers for Membrane Transduction and Mitochondrial Localization
Biomacromolecules, 7, 2347-2356 (2006)
340. J. Yang, C. Xu, C. Wang, J. Kopecek
Refolding hydrogels Self-Assembled from HPMA Graft Copolymers by Antiparallel Coiled Coil Formation
Biomacromolecules, 7, 1187-1195 (2006)
339. H. Ding, W. Prodinger, J. Kopecek
Identification of CD21-Binding Peptides with Phage Display and Investigation of Binding Properties of HPMA Copolymer - Peptide Conjugates
Bioconjugate Chem., 17, 514-523 (2006)
338. H. Pan, P. Kopeckova, D. Wang, J. Yuan, S. Miller, J. Kopecek
Water-Soluble HPMA Copolymer - Prostaglandin Conjugates Containing a Cathepsin K Sensitive Spacer
J. Drug Targeting, 14, 425-435 (2006)
337. J. Yang, C. Xu, P. Kopeckova, J. Kopecek
Hybrid Hydrogels Self-Assembled from HPMA Copolymers Containing Peptide Grafts
Macromol. Biosci., 6, 201-209 (2006)
336. A. Malugin, P. Kopeckova, J. Kopecek
HPMA Copolymer-Bound Doxorubicin Induces Apoptosis in Ovarian Carcinoma Cells by the Disruption of Mitochondrial Function
Molecular Pharmaceutics, 3, 351-361 (2006)
335. V. Cuchelkar, J. Kopecek
Polymer-Drug Conjugates
In: Polymers in Drug Delivery, I.F. Uchegbu, Ed., CRC Press, Boca Raton, Florida, 2006, pp. 155-182
334. S.-Q. Gao, Z.-R. Lu, B. Petri, P. Kopeckova, J. Kopecek
Colon-Specific 9-Aminocamptothecin - HPMA Copolymer Conjugates Containing a 1,6-Elimination Spacer
J. Contr. Rel., 110, 323-331 (2006)
333. P. Chivukula, K. Dusek, D. Wang, M. Duskova-Smrckova, P. Kopeckova, J. Kopecek
Synthesis and Characterization of Novel Aromatic Azo Bond-Containing pH-Sensitive and Hydrolytically Cleavable IPN Hydrogels
Biomaterials, 27, 1140-1151 (2006)
332. T. Merdan, K. Kunath, H. Petersen, U. Bakowsky, K.H. Voigt, J. Kopecek, T. Kissel
PEGylation of Poly(ethylene imine) Affects Stability of Complexes with Plasmid DNA Under In Vivo Conditions in a Dose-Dependent Manner after Intravenous Injection into Mice
Bioconjugate Chem. 16, 785-792 (2005)
331. R.M. Hyde, K. Jensen, J. Kopecek, A.D. Broom
Confocal Microscopy Studies of a Model Oligoribonucleotide HIV Inhibitor
Nucleosides, Nucleotides, Nucl. Acids, 24, 1875-1884 (2005)
330. C. Xu, V. Breedveld, J. Kopecek
Reversible Hydrogels from Self-Assembling Genetically Engineered Protein Block Copolymers
Biomacromolecules, 6, 1739-1749 (2005)
329. D. Wang, S. Miller, P. Kopeckova, J. Kopecek
Bone-Targeting Macromolecular Therapeutics
Adv. Drug Delivery Rev., 57, 1049-1076 (2005)
328. A. Nori, J. Kopecek
Intracellular Targeting of Polymer-Bound Drugs for Cancer Chemotherapy
Adv. Drug Delivery Rev., 57, 609-636 (2005)
327. S.C. Miller, D. Wang, P. Kopeckova, J. Kopecek
Biopolymer-Based Delivery System for Advanced Imaging and Skeletal Tissue-Specific Therapeutics
J. Bone Mineral Metabolism, 23(suppl), 103-108 (2005)
326. P.D. Senter, J. Kopecek
Drug Carriers in Medicine and Biology
Molecular Pharmaceutics 1, 395-398 (2004)
325. J. Kopecek
Genetically Engineered Protein Motifs in the Design of Novel Polymers and Drug Delivery Systems
In: Contemporary Topics in Advanced Polymer Science and Technology, Q.-F. Zhou, S.Z.D. Cheng, Eds., Peking University Press, pp. 374-386 (2004)
324. D. Wang, S.C. Miller, M. Sima, D. Parker, H. Buswell, C. Goodrich, P. Kopeckova,
J. Kopecek
The Arthrotropism of Macromolecules in Adjuvant Induced Arthritis Rat Model – A Preliminary Study
Pharmaceutical Res., 21, 1741-1749 (2004)
323. A. Malugin, P. Kopeckova, J. Kopecek
HPMA Copolymer-Bound Doxorubicin Induces Apoptosis in Human Ovarian Carcinoma Cells by a Fas Independent Pathway
Molecular Pharmaceutics, 1, 174-182 (2004)
322. D. Wang, W. Li, M. Pechar, P. Kopeckova, D. Brömme, J. Kopecek
Cathepsin K Inhibitor – Polymer Conjugates: Potential Drugs for the Treatment of Osteoporosis and Rheumatoid Arthritis
Int. J. Pharm., 277, 73-79 (2004)
321. A. David, P. Kopeckova, T. Minko, A. Rubinstein, J. Kopecek
Design of a Multivalent Galactoside Ligand for Selective Targeting of HPMA Copolymer-Doxorubicin Conjugates to Human Colon Cancer Cells
Eur. J. Cancer, 40, 148-157 (2004)
320. K. Dusek, M. Duskova-Smrckova, M. Ilavsky, R. Stewart, J. Kopecek
Swelling Presure Induced Phase-Volume Transition in Hybrid Biopolymer Gels Caused by Unfolding of Folded Crosslinks: A Model
Biomacromolecules, 4, 1818-1826 (2003)
319. N. Nishiyama, A. Nori, A. Malugin, Y. Kasuya, P. Kopeckova, J. Kopecek
Free and N-(2-Hydroxypropyl)methacrylamide (HPMA) Copolymer-bound Geldanamycin Derivative Induce Different Stress Responses in A2780 Human Ovarian Carcinoma Cells
Cancer Res., 63, 7876-7882 (2003)
318. D. Wang, S. Miller, M. Sima, P. Kopeckova, J. Kopecek
Synthesis and Evaluation of Water-Soluble Polymeric Bone-Targeted Drug Delivery Systems
Bioconjugate Chem., 14, 853-859 (2003)
 317. T. Merdan, J. Callahan, H. Petersen, K. Kunath, U. Bakowsky, P. Kopeckova, T. Kissel, J. Kopecek
Pegylated Polyethylenimine – Fab’ Antibody Fragment Conjugates for Targeted Gene Delivery to Human Ovarian Carcinoma Cells
Bioconjugate Chem., 14, 989-996 (2003)
316. J. Kopecek, P. Kopeckova
Macromolecular Therapeutics: State-of-the-Art and Future Potential
Bulletin Technique Gattefossé 96, 9-21 (2003
 315. J. Kopecek
Smart and Genetically Engineered Biomaterials and Drug Delivery Systems
Eur. J. Pharm.Sci., 20, 1-16 (2003)
 314.  Z.-R. Lu, P. Kopeckova, J. Kopecek
Antigen Responsive Hydrogels Based on Polymerizable Antibody Fab’ Fragment
Macromol. Biosci., 3, 296-300 (2003)
Bulletin Technique Gattefossé 96, 9-21 (2003)
 313. A. Nori, K.D. Jensen, M. Tijerina, P. Kopeckova, J. Kopecek
Subcellular Trafficking of HPMA Copolymer-TAT Conjugates in Human Ovarian Carcinoma Cells
J. Contr. Rel., 91, 53-59 (2003)
 312. M. Tijerina, P. Kopeckova, J. Kopecek
Mechanisms of Cytotoxicity in Human Ovarian Carcinoma Cells Exposed to Free Mce6 or HPMA Copolymer-Mce6 Conjugates
Photochem. Photobiol., 77, 645-652 (2003)
 311. M. Tijerina, P. Kopeckova, J. Kopecek
Correlation of Subcellular Compartmentalization of HPMA Copolymer-Mce6 Conjugates with Chemotherapeutic Activity in Human Ovarian Carcinoma Cells
Pharmaceutical Res., 20, 728-737 (2003)
 310.  C.M. Peterson, J.G. Shiah, Y. Sun, P. Kopeckova, T. Minko, R.C. Straight, J. Kopecek
HPMA Copolymer Delivery of Chemotherapy and Photodynamic Therapy in Ovarian Cancer
Adv. Exp. Med. Biol. 519, 101-123 (2003)
 309. A. Tang, P. Kopeckova, J. Kopecek
Binding and Cytotoxicity of HPMA Copolymer Conjugates to Lymphocytes Mediated by Receptor-binding Epitopes
Pharmaceutical Res., 20, 360-367 (2003)
 308.  A. Nori, K.D. Jensen, M. Tijerina, P. Kopeckova, J. Kopecek
Tat Conjugated Synthetic Macromolecules Facilitate Cytoplasmic Drug Delivery to Human Ovarian Carcinoma Cells
Bioconjugate Chem., 14, 44-50 (2003)
 307.  K.D. Jensen, A. Nori, M. Tijerina, P. Kopeckova, J. Kopecek
Cytoplasmic Delivery and Nuclear Targeting of Synthetic Macromolecules
J. Contr. Rel., 87, 89-105 (2003)
 306. Z.-R. Lu, J.-G. Shiah, P. Kopeckova, J. Kopecek
Polymerizable Fab’ Antibody Fragment Targeted Photodynamic Cancer Therapy in Nude Mice
STP Pharma Sci., 13, 69-75 (2003)
 305. T. Merdan, J. Kopecek, T. Kissel
Prospects for Cationic Polymers in Gene and Oligonucleotide Therapy against Cancer
Adv. Drug Delivery Rev., 54, 715-758 (2002)
 304. J. Kopecek
Swell Gels (News and Views)
Nature 417, 388-391 (2002)
 303. S. Sakuma, Z.-R. Lu, B. Pecharova, P. Kopeckova, J. Kopecek
N-(2-Hydroxypropyl)methacrylamide Copolymer – 9-Aminocamptothecin Conjugate: Colon-Specific Delivery in Rats
J. Bioact. Comp. Polym., 17, 305-319 (2002)
 302. D. Wang, K. Dusek, P. Kopeckova, M. Smrckova-Duskova, J. Kopecek
Novel Aromatic Azo-Containing pH-Sensitive Hydrogels: Synthesis and Characterization
Macromolecules, 35, 7791-7803 (2002)
 301.  K.D. Jensen, P. Kopeckova, J. Kopecek
Antisense Oligonucleotides Delivered to the Lysosome Escape and Actively Inhibit the Hepatitis B Virus
Bioconjugate Chem., 13, 975-984 (2002)
300.  D. Wang, M. Pechar, W. Li, P. Kopeckova, D. Brömme, J. Kopecek
Inhibition of Cathepsin K with Lysosomotropic Macromolecular Inhibitors
Biochemistry, 41, 8849-8859 (2002)
 299. M. Pechar, P. Kopeckova, L. Joss, J. Kopecek
Associative Diblock Copolymers of Poly(Ethylene Glycol) and Coiled Coil Peptides
Macromol. Biosci., 2, 199-206 (2002)
 298. T. Merdan, K. Kunath, D. Fischer, J. Kopecek, T. Kissel
Intracellular Processing of Poly(ethylene imine)/Ribozyme Complexes Can Be Observed in Living Cells Using Confocal Laser Scanning Microscopy and Inhibitor Experiments
Pharmaceutical Res., 19, 140-146 (2002)
 297.  C. Xu, C. Wang, M. Pechar, J. Kopecek
The Influence of the Fusion Sequence on the Thermal Stability of Genetically Engineered Coiled-Coil Peptides, Macromol. Biosci., 2, 395-401 (2002)
 296. Y. Luo, N.J. Bernshaw, Z.-R. Lu, J. Kopecek, G.D. Prestwich
Targeted Delivery of HPMA Copolymer – Hyaluronan – Doxorubicin Bioconjugates
Pharmaceutical Res., 19, 396-402 (2002)
 295. A. Tang, J. Kopecek
Presentations of Epitopes on Peptide Scaffolds and Selection of Lymphoma-Targeting Moieties Based on Epitope Recognition
Biomacromolecules, 3. 421-431 (2002)
 294. K.D. Jensen, P. Kopeckova, J.H.B. Bridge, J. Kopecek
The Cytoplasmic Escape and Nuclear Accumulation of Endocytosed and Microinjected HPMA Copolymers and a Basic Kinetic Study in HepG2 Cells
AAPS PharmSci, Volume 3, Issue 4, paper 32 (2002)
 293. Z.-R. Lu, J.-G. Shiah, S. Sakuma, P. Kopeckova, J. Kopecek
Design of Novel Conjugates for Targeted Drug Delivery
J. Contr. Rel., 78, 165-173 (2002)
 292. Y. Kasuya, Z.-R. Lu, P. Kopeckova, S.E. Tabibi, J. Kopecek
Influence of the Structure of Drug Moieties on the In Vitro Efficacy of HPMA Copolymer-Geldanamycin Derivative Conjugates
Pharmaceutical Res., 19, 115-123 (2002)
291. A. David, P. Kopeckova, J. Kopecek, A. Rubinstein
The Role of Galactose, Lactose and their Three-Dimensional Arrangement in the Biorecognition of HPMA Copolymers by Human Colon Adenocarcinoma Cells
Pharmaceutical Res., 19, 1114-1122 (2002)
 290.  S. Sakuma, Z.-R. Lu, P. Kopeckova, J. Kopecek
Biorecognizable HPMA Copolymer-Drug Conjugates for Colon-Specific Delivery of 9-Aminocamptothecin
J. Contr. Rel., 75, 365-379 (2001)
 289. C. Wang, J. Kopecek R.J. Stewart
Hybrid Hydrogels Crosslinked by Genetically Engineered Coiled-coil Block Proteins
Biomacromolecules, 2, 912-920 (2001)
 288. Y. Kasuya, Z.-R. Lu, P. Kopeckova, J. Kopecek
Improved Synthesis and Evaluation of 17-Substituted Aminogeldanamycin Derivatives Applicable to Drug Delivery Systems
Bioorg. Med. Chem. Lett., 11, 2089-2091 (2001)
 287. K. Dusek, M. Duskova-Smrckova, R. Stewart, J. Kopecek
A Model for Swelling Changes in a Covalently Crossliked Gel Caused by Unfolding of Folded Domains
Polymer Bull., 47, 351-358 (2001)
 286. J.-G. Shiah, Y. Sun, P. Kopeckova, C.M. Peterson, R.C. Straight, J. Kopecek
Combination Chemotherapy and Photodynamic Therapy of Targetable N-(2-Hydroxypropyl)methacrylamide Copolymer–Doxorubicin/Mesochlorin e6-OV-TL16 Antibody Immunoconjugates
J. Contr. Rel., 74, 249-253 (2001)
 285. Z.-R. Lu, J.-G. Shiah, P. Kopeckova, J. Kopecek
Preparation and Biological Evaluation of Polymerizable Antibody Fab' Fragment Targeted Polymeric Drug Delivery System
J. Contr. Rel., 74, 263-268 (2001)
 284. S. Wroblewski, M. Berenson, P. Kopeckova, J. Kopecek
Potential of Lectin – N-(2-Hydroxypropyl)methacrylamide Copolymer – Drug Conjugates for the Treatment of Pre-Cancerous Conditions
J. Contr. Rel., 74, 283-293 (2001)
 283. M. Tijerina, P. Kopeckova, J. Kopecek
The Effects of Subcellular Localization of N-(2-Hydroxypropyl)methacrylamide Copolymer-Mce6 Conjugates in a Human Ovaian Carcinoma
J. Contr. Rel., 74, 269-273 (2001)
 282.  L. Varticovski, Z.-R. Lu, I. De Aos, K. Mitchell, R. Christensen, J. Kopecek
A Water-Soluble HPMA Copolymer – Wortmannin Conjugate Retains Phosphoinositide 3-Kinase Inhibitory Activity In Vitro and In Vivo
J. Contr. Rel., 74, 275-281 (2001)
 281. A. David, P. Kopeckova, A. Rubinstein, J. Kopecek
Enhanced Biorecognition and Internalization of HPMA Copolymers Containing Multi- or Multivalent Carbohydrate Side-Chains by Human Hepatocarcinoma Cells
Bioconjugate Chem., 12, 890-899 (2001)
 280. K.D. Fowers, J. Callahan, P. Byron, and J. Kopecek
Preparation of Fab' from Murine IgG2a for Thiol Reactive Conjugation
J. Drug Targeting, 9, 281-294 (2001)
 279. C. Konak, B. Ganchev, M. Teodorescu, K. Matyjaszewski, P. Kopeckova, J. Kopecek
Poly[N-(2-Hydroxypropyl)methacrylamide-block-n-Butyl Acrylate] Micelles in Water/DMF Mixed Solvents
Polymer, 43, 3735-3741 (2002)
 278. Y. Kasuya, Z.-R. Lu, P. Kopeckova, T. Minko, S.E. Tabibi, J. Kopecek
Synthesis and Characterization of HPMA Copolymer – Aminopropylgeldanamycin Conjugates
J. Contr. Rel., 74, 203-211 (2001)
 277. J. Kopecek, P. Kopeckova, T. Minko, Z.-R. Lu, C.M. Peterson
Water Soluble Polymers in Tumor Targeted Delivery
J. Contr. Rel., 74, 147-158 (2001)
 276. J. Kopecek, A. Tang, C. Wang, R.J. Stewart
De Novo Design of Biomedical Polymers: Hybrids from Synthetic Macromolecules and Genetically Engineered Protein Domains
Macromolecular Symposia, 174, 31-42 (2001)
 275.  S. Wroblewski, B. Rihova, P. Rossmann, T. Hudcovicz, Z. Rehakova, P. Kopeckova, J. Kopecek
The Influence of a Colonic Microbiota on HPMA Copolymer – Lectin Conjugates Binding in Rodent Intestine
J. Drug Targeting, 9, 85-94 (2001)
 274. Z.-R. Lu, S.-Q. Gao, P. Kopeckova, J. Kopecek
Modification of Cyclosporin A and Conjugation of Its Derivative to HPMA Copolymers
Bioconjugate Chem., 12, 129-133 (2001)
 273. T. Minko, P. Kopeckova, J. Kopecek
The Role of Caspases in Apoptosis Induced by Free and HPMA Copolymer-Bound Doxorubicin in Human Ovarian Carcinoma Cells
J. Contr. Rel., 71, 227-237 (2001)
 272. J.-G. Shiah, M. Dvorak, P. Kopeckova, Y. Sun, C.M. Peterson, J. Kopecek
Biodistribution and Antitumor Efficacy of Long-Circulating N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates in Nude Mice
Eur. J. Cancer, 37, 131-139 (2001)
 271.  A. Tang, C. Wang, R.J. Stewart, J. Kopecek
The Coiled Coil in the Design of Protein-Based Constructs: Hybrid Hydrogels and Epitope Displays
J. Contr. Rel., 72, 57-70 (2001)
 270.  T. Minko, P. Kopeckova, J. Kopecek
Mechanism of Anticancer Action of HPMA Copolymer-Bound Doxorubicin
Macromolecular Symposia, 172, 35-47 (2001)
 269.  Z.-R. Lu, P. Kopeckova, J. Kopecek
Semitelechelic Poly[N-(2-hydroxypropyl)methacrylamide] for Biomedical
Applications, In: Polymeric Drugs & Delivery Systems, R.M. Ottenbrite, S.W. Kim, Eds., Technomics Publishing Co., Lancaster, PA, 2001, pp. 1-14
 268.  C. Wang, R.J. Stewart, J. Kopecek
Genetically Engineered Protein Domain as Crosslinks in Hydrogels, In: Polymeric Drugs & Delivery Systems, R.M., Ottenbrite, S.W. Kim, Eds., Technomics Publishing Co., Lancaster, PA, 2001, pp. 131-143
 267. D. Wang, P. Kopeckova, T. Minko, V. Nanayakkara, J. Kopecek
Synthesis of Star-Like N-(2-Hydroxypropyl)methacrylamide Copolymers – Potential Drug Carriers
Biomacromolecules, 1, 313-319 (2000)
  266. L. Chen, J. Kopecek, R.J. Stewart
Responsive Hybrid Hydrogels with Volume Transitions Modulated by a Titin Immunoglobulin Module
Bioconjugate Chem., 11, 734-740 (2000)
 265.  M. Tijerina, K. Fowers, P. Kopeckova, J. Kopecek
Chronic Exposure of Human Ovarian Carcinoma Cells to Free or HPMA Copolymer-Bound Mesochlorin e6 Does Not Induce P-Glycoprotein Mediated Multidrug Resistance
Biomaterials, 21, 2203-2210 (2000)
 264.  S. Wroblewski, M. Berenson, P. Kopeckova, J. Kopecek
Biorecognition of HPMA Copolymer-Lectin Conjugates as an Indicator of Differentiation of Cell-Surface Glycoproteins in Development, Maturation and Diseases of Human and Rodent Gastrointestinal Tissues
J. Biomed. Mater. Res., 51, 329-342 (2000)
 263.  M. Demoy, T. Minko, P. Kopeckova, J. Kopecek
Time- and Concentration-Dependent Apoptosis and Necrosis Induced by Free and HPMA Copolymer-Bound Doxorubicin in Human Ovarian Carcinoma Cells, J. Contr. Rel., 69, 185-196 (2000)
 262.  J. Kopecek, P. Kopeckova, T, Minko, Z.-R. Lu
HPMA Copolymer – Anticancer Drug Conjugates: Design, Activity, and Mechanism of Action
Eur. J. Pharmaceutics Biopharm., 50, 61-81 (2000)
 261.  T. Minko, P. Kopeckova, V. Pozharov, K. Jensen, J. Kopecek
The Influence of Cytotoxicity of Macromolecules and of VEFG Gene Modulated Vascular Permeability on the Enhanced Permeability and Retention Effect in Resistant Solid Tumor
Pharmaceutical Res., 17, 505-514 (2000)
 260. A. Tang, C. Wang, R. Stewart, J. Kopecek
Self-Assembled Peptides Exposing Epitopes Recognizable by Human Lymphoma Cells
Bioconjugate Chem., 11, 363-371 (2000)
 259. Z.-R. Lu, S.-Q. Gao, P. Kopeckova, J. Kopecek
Synthesis of Bioadhesive Lectin – HPMA Copolymer – Cyclosporin Conjugates
Bioconjugate Chem., 11, 3-7 (2000)
 258. T. Minko, P. Kopeckova, J. Kopecek
Efficacy of Chemotherapeutic Action of HPMA Copolymer-Bound Doxorubicin in a Solid Tumor Model of Ovarian Carcinoma
Int. J. Cancer, 86, 108-117 (2000)
 257. P.R. Hart, P. Kopeckova, V. Omelyanenko, E. Enioutina, J. Kopecek
HPMA Copolymer-Modified Avidin: Immune Response,
J. Biomat. Sci., Polym. Ed., 11, 1-12 (2000)
 256. J.-G. Shiah, Y. Sun, C.M. Peterson, R.C. Straight, J. Kopecek
Antitumor Activity of HPMA Copolymer-Meso Chlorin e6 and Adriamycin Conjugates in Combination Treatments, Clin., Cancer Res., 6, 1008-1015 (2000)
 255.  H.-R. Shen, J.D. Spikes, C.J. Smith, J. Kopecek
Photodynamic Crosslinking of Proteins. V. Nature of the Tyrosine-Tyrosine Bonds Formed in the FMN-sensitized Intermolecular Crosslinking of N-Acetyl-L-Tyrosine
J.Photochem. Photobiol., A: Chem., 133, 115-122 (2000) 
 254. K. Kunath, P. Kopeckova, T. Minko, J. Kopecek
HPMA Copolymer – Anticancer Drug - OV-TL16 Antibody Conjugates. 3. The Effect of Free and Polymer-bound Adriamycin on the Expression of Some Genes in the OVCAR-3 Human Ovarian Carcinoma Cell Line
Eur. J. Pharmaceutics Biopharm., 49, 11-15 (2000)
 253.  W.-M. Choi, P. Kopeckova, T. Minko, J. Kopecek
Synthesis of HPMA Copolymer Containing Adriamycin Bound via an Acid-labile
Spacer and its Activity toward Human Ovarian Carcinoma Cells
J. Bioact. Comp. Polym., 14, 447-456 (1999)
 252.  J.M. Lu, C.M. Peterson, J.G. Shiah, Z.-W. Gu, C.A. Peterson, R.C.Straight, J. Kopecek
Cooperativity between Free and N-(2-Hydroxypropyl)methacrylamide Copolymer Bound Adriamycin and Mesochlorin e6 Monoethylene Diamine Induced Photodynamic Therapy in Human Epithelial Ovarian Carcinoma In Vivo,
Int. J. Oncology, 15, 5-16 (1999)
 251.  J.-G. Shiah, Y. Sun, C.M. Peterson, J. Kopecek
Biodistribution of Free and N-(2-Hydroxypropyl)methacrylamide Copolymer-Bound Meso Chlorin e6 and Adriamycin in Nude Mice Bearing Human Ovarian Carcinoma OVCAR-3 Xenografts,
J. Contr. Rel., 61, 145-157 (1999)
 250.  Z.-R. Lu, P. Kopeckova, J. Kopecek
Polymerizable Fab' Antibody Fragment for Targeting of Anticancer Drugs,
Nature Biotechnology, 17, 1101-1104 (1999)
 249. M. Dvorak, P. Kopeckova, J. Kopecek
High-Molecular Weight HPMA Copolymer-Adriamycin Conjugates,
J. Contr. Rel., 60, 321-332 (1999)
 248.  H.-R. Shen, J.D. Spikes, C.J. Smith, J. Kopecek
Photodynamic Crosslinking of Proteins. IV. Nature of the His-His Bond(s) Formed in the Rose Bengal-photosensitized Crosslinking of N-Benzoyl-L-Histidine,
J. Photochem. Photobiol., A: Chem., 130, 1-6 (1999)
 247. Z.-R. Lu, P. Kopeckova, Z. Wu, J. Kopecek
Synthesis of Semitelechelic Poly[N-(2-Hydroxypropyl)methacrylamide] by Radical Polymerization in the Presence of Alkyl Mercaptans
Macromol. Chem. Phys., 200, 2022-2030 (1999)
 246. T. Minko, P. Kopeckova, J. Kopecek
Comparison of the Anticancer Effect of Free and HPMA Copolymer Bound Adriamycin in Human Ovarian Carcinoma cells,
Pharmaceutical Res., 16, 986-996 (1999)
 245. V. Omelyanenko, P. Kopeckova, R.K. Prakash, C.D. Ebert, J. Kopecek
Biorecognition of HPMA Copolymers by Lymphocytes Mediated by Synthetic Receptor Binding Epitopes,
Pharmaceutical Res., 16, 1010-1019 (1999)
 244. J.D. Spikes, H.-R. Shen, P. Kopeckova, J. Kopecek
Photodynamic Crosslinking of Proteins. III. Kinetics of the FMN- and Rose Bengal- sensitized Photooxidation and Intermolecular Crosslinking of Model Tyrosine- containing N-(2-Hydroxypropyl)methacrylamide Copolymers,
Photochem. Photobiol., 70, 130-137 (1999)
 243. C. Wang, R.J. Stewart, J. Kopecek
Hybrid Hydrogels Assembled from Synthetic Polymers and Coiled-Coil Protein Domains
Nature, 397, 417-420 (1999)
 242. R.H. Lu, P. Kopeckova, J. Kopecek
Degradation and Aggregation of Human Calcitonin
Pharmaceutical Res., 16, 359-367 (1999) 
 241.  T. Minko, P. Kopeckova, J. Kopecek
Chronic Exposure to HPMA Copolymer-bound Adriamycin does not Induce Multidrug resistance in a Human Ovarian Carcinoma Cell Line
J. Contr. Rel., 59, 133-148 (1999)
 240. Z.-R. Lu, P. Kopeckova, Z. Wu, J. Kopecek
Functionalized Semitelechelic Poly[N-(2-Hydroxypropyl)methacrylamide] for Protein Modification
Bioconjugate Chem., 9, 793-804 (1998)
 239. C. Konak, M. Helmstedt, P. Kopeckova, J. Kopecek
Micellization of Graft Copolymers of Alkyl Methacrylates with alpha-Methyl-omega-Hydroxy-Poly(oxyethylene) Methacrylates
J. Coll. Interface Sci., 208, 252-258 (1998)
 238. C. Konak, R.C. Rathi, P. Kopeckova, J. Kopecek
Photoassociation of Water-Soluble Copolymers Containing Photochromic Spirobenzopyran Moieties
Adv. Polym. Technologies, 9, 641-648 (1998)
 237. S. Wroblewski, P. Kopeckova, B. Rihova, J. Kopecek
Lectin - HPMA Copolymer Conjugates: Potential Oral Drug Carriers for Targeting Diseased Tissues
Macromol. Chem. Phys., 199, 2601-2608 (1998)
 236. E.O. Akala, P. Kopeckova, J. Kopecek
Novel pH Sensitive Hydrogels with Adjustable Swelling Kinetics
Biomaterials, 19, 1037-1047 (1998)
 235.  J.-G. Shiah, C. Konak, J. D. Spikes, J. Kopecek
Influence of pH on Solubility and Photoproperties of N-(2-Hydroxypropyl)methacrylamide Copolymer - Meso-Chlorin e6 Conjugates
Drug Delivery, 5, 119-126 (1998)
 234.  T. Minko, P. Kopeckova, V. Pozharov, J. Kopecek
HPMA Copolymer Bound Adriamycin Overcomes MDR1 Gene Encoded Resistance in a Human Ovarian Carcinoma Cell Line
J. Contr. Rel., 54, 223-233 (1998)
 233.  V. Omelyanenko, C. Gentry, P. Kopeckova, J. Kopecek
HPMA Copolymer - Anticancer Drug - OV-TL16 Antibody Conjugates. 2. Processing in Epithelial Ovarian Carcinoma Cells In Vitro
Int. J. Cancer, 75, 600-608 (1998)
 232.  V. Omelyanenko, P. Kopeckova, C. Gentry, J. Kopecek
Targetable HPMA Copolymer - Adriamycin Conjugates. Recognition, Internalization, and Subcellular Fate
J. Contr. Rel., 53, 25-38 (1998)
 231.  J. Kopecek, P. Kopeckova, C. Konak
Biorecognizable Polymers: Design, Structure, and Bioactivity
J. Macromol. Sci., A - Pure Appl. Chem., A34, 2103-2117 (1997)
 230.  J.-G. Shiah, C. Konak, J.D. Spikes, J. Kopecek
Solution and Photoproperties of N-(2-Hydroxypropyl)methacrylamide Copolymer - Meso-Chlorin e6 Conjugates
J. Phys. Chem. B, 101, 6803-6809 (1997)
 229.  C. Konak, R.C. Rathi, P. Kopeckova, J. Kopecek
Photoregulated Association of Water-Soluble Copolymers with Spirobenzopyran-Containing Side Chains
Macromolecules, 30, 5553-5556 (1997)
 228.  K.D. Fowers, J. Kopecek
Development of a Fibrinolytic Surface: Specific and Non-Specific Binding of Plasminogen
Colloids Surfaces, B: Biointerfaces, 9, 315-330 (1997)
 227.  H. Ghandehari, P.L. Smith, H. Ellens, P.-Y. Yeh, J. Kopecek
Size-Dependent Permeability of Hydrophilic Probes Across Rabbit Colonic Epithelium
J. Pharmacol. Exp. Ther., 280, 747-753 (1997)
 226.  H. Ghandehari, P. Kopeckova, J. Kopecek
In Vitro Degradation of pH Sensitive Hydrogels Containing Aromatic Azo Bonds
Biomaterials, 18, 861-872 (1997)
 225.  R.C. Rathi, P. Kopeckova, J. Kopecek
Biorecognition of Sugar Containing N-(2-Hydroxypropyl)methacrylamide Copolymers by Immobilized Lectin
Macromol. Chem. Phys., 198, 1165-1180 (1997)
 224.  H.-C. Chiu, P. Kopeckova, S.S. Deshmane, J. Kopecek
Lysosomal Degradation of Poly(alpha-Amino Acids)
J. Biomed. Mater. Res., 34, 381-392 (1997)
 223.  D. Putnam, J.-G. Shiah, J. Kopecek
Intracellularly Biorecognizable Derivatives of 5-Fluorouracil: Implications of Targetable Delivery in the Human Condition
Biochem. Pharmacol., 52, 957-962 (1996)
 222.  H.-R. Shen, J.D. Spikes, P. Kopeckova, J. Kopecek
Photodynamic Crosslinking of Proteins. 2. Photocrosslinking of a Model Protein - Ribonuclease A
J. Photochem. Photobiol., B: Biol., 35, 213-219 (1996)
 221.  H.-R. Shen, J.D. Spikes, P. Kopeckova, J. Kopecek
Photodynamic Crosslinking of Proteins. 1. Model Studies Using Histidine- and Lysine-Containing N-(2-Hydroxypropyl)methacrylamide Copolymers
J. Photochem. Photobiol., B: Biol., 34, 203-210 (1996)
 220.  C.M. Peterson, J.M. Lu, Y. Sun, C.A. Peterson, J.-G. Shiah, R.C. Straight, J. Kopecek
Combination Chemotherapy and Photodynamic Therapy with N-(2-Hydroxypropyl)methacrylamide Copolymer-bound Anticancer Drugs Inhibit Human Ovarian Carcinoma Heterotransplanted in Nude Mice
Cancer Res., 56, 3980-3985 (1996)
 219.  V. Omelyanenko, P. Kopeckova, C. Gentry, J.-G. Shiah, J. Kopecek
HPMA Copolymer - Anticancer Drug - OV-TL16 Antibody Conjugates. 1. Influence of the Method of Synthesis on the Binding Affinity to OVCAR-3 Ovarian Carcinoma Cells In Vitro
J. Drug Targeting, 3, 357-373 (1996)
 218.  J. Kopecek, P. Kopeckova, V. Omelyanenko
Biorecognizable Biomedical Polymers
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 217.  H. Ghandehari, P. Kopeckova, P.-Y. Yeh, J. Kopecek
Biodegradable and pH Sensitive Hydrogels: Synthesis by a Polymer - Polymer Reaction
Macromol. Chem. Phys., 197, 965-980 (1996)
 216.  C.M. Peterson, J.M. Lu, Z.-W. Gu, J.-G. Shiah, K. Lythgoe, C.A. Peterson, J. Kopecek
Isobolographic Assessment of the Interaction between Adriamycin and Photodynamic Therapy with meso-Chlorin e6 Monoethylene Diamine in Human Epithelial Ovarian Carcinoma (OVCAR-3) In Vitro
J. Soc. Gynecol. Invest., 2, 772-777 (1995)
 215.  D. Putnam, J. Kopecek
Enantioselective Release of 5-Fluorouracil from HPMA Based Copolymers via Lysosomal Enzymes
Bioconjugate Chem., 6, 483-492 (1995)
 214.  Z.-W. Gu, V. Omelyanenko, P. Kopeckova, J. Kopecek, C. Konak
Association of a Substituted Zinc(II) Phthalocyanine - N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugate
Macromolecules, 28, 8375-8380 (1995)
 213.  C. Konak, Z. Tuzar, P. Kopeckova, J.D. Andrade, J. Kopecek
Association of Graft Copolymers of Alkyl Methacrylates with alpha-Methyl-omega-Hydroxy-Poly(Oxyethylene) Methacrylates
Collection Czechoslov. Chem. Commun., 60, 1971-1985 (1995)
 212.  P.-Y. Yeh, P. Kopeckova, J. Kopecek
Degradability of Hydrogels Containing Azoaromatic Crosslinks
Macromol. Chem. Phys., 196, 2183-2202 (1995)
 211.  S. Kamei, J. Kopecek
Prolonged Blood Circulation in Rats of Nanospheres Surface-Modified with Semitelechelic Poly[N-(2-Hydroxypropyl)methacrylamide]
Pharm. Res., 12, 663-668 (1995)
 210.  P.-Y. Yeh, M.M. Berenson, W.S. Samowitz, P. Kopeckova, J. Kopecek
Site-Specific Drug Delivery and Penetration Enhancement in the Gastrointestinal Tract
J. Contr. Rel., 36, 109-124 (1995)
 209.  D. Putnam, J. Kopecek
Polymer Conjugates with Anticancer Activity
Adv. Polym. Sci., 122, 55-123 (1995)
 208.  H.-C. Chiu, C. Konak, P. Kopeckova, J. Kopecek
Enzymatic Degradation of Poly(Ethylene Glycol) Modified Dextrans
J. Bioact. Comp. Polym., 9, 388-410 (1994)
 207.  C. Konak, P. Kopeckova, J. Kopecek
Photoregulated Adsorption and Association of Amphiphilic Copolymers Containing Azobenzene Side-Chains
J. Coll. Interface Sci., 168, 235-241 (1994)
 206.  C. Konak, R.C. Rathi, P. Kopeckova, J. Kopecek
Solution Properties of Polymers Containing Zwitterionic Moieties in Side-Chains
Macromolecules, 27, 1992-1996 (1994)
 205.  P.-Y. Yeh, P. Kopeckova, J. Kopecek
Biodegradable and pH Sensitive Hydrogels: Synthesis by Crosslinking of N,N-Dimethylacrylamide Copolymer Precursors
J. Polym. Sci., Part A: Polym. Chem., 32, 1627-1637 (1994)
 204.  H.-R.H. Yen, S. Oscarsson, K. Ulbrich, J. Kopecek
Adsorption and Activation of Zymogens at Solid-Liquid Interfaces. I. Chymotrypsinogen on Alkylamino Modified Silica Derivatives
J. Biomed. Mater. Res., 28, 247-257 (1994)
 203.  P. Kopeckova, R.C. Rathi, S. Takada, B. Rihova, M.M. Berenson, J. Kopecek
Bioadhesive N-(2-Hydroxypropyl)methacrylamide Copolymers for Colon-Specific Drug Delivery
J. Contr. Rel., 28, 211-222 (1994)
 202.  N.L. Krinick, Y. Sun, D. Joyner, J.D. Spikes, R.C. Straight, J. Kopecek
A Polymeric Drug Delivery System for the Simultaneous Delivery of Drugs Activatable by Enzymes and/or Light
J. Biomat. Sci., Polym. Ed., 5, 303-324 (1994)
 201.  Z.-W. Gu, J.D. Spikes, P. Kopeckova, J. Kopecek
Synthesis and Photoproperties of a Substituted Zinc (II) Phthalocyanine - N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugate
Collection Czechoslov. Chem. Commun., 58, 2321-2336 (1993)
 200.  H.-C. Chiu, S. Zalipsky, P. Kopeckova, J. Kopecek
Enzymatic Activity of Chymotrypsin and its Poly(Ethylene Glycol) Conjugates Toward Low and High Molecular Weight Substrates
Bioconjugate Chem., 4, 290-295 (1993)
 199.  J.D. Spikes, N.L. Krinick, J. Kopecek
Photoproperties of a Mesochlorin e6 - N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugate
J. Photochem. Photobiol., A:Chem., 70, 163-170 (1993)
 198.  C. Konak, R.C. Rathi, P. Kopeckova, J. Kopecek
Effect of Side-Chains on Solution Properties of N-(2-Hydroxypropyl)methacrylamide Copolymers in Aqueous Solvents
Polymer, 34, 4767-4773 (1993)
 197.  B. Rihova, N.L. Krinick, J. Kopecek
Targetable Photoactivatable Drugs. 3. Specific In Vitro Destruction of a Human Hepatocarcinoma Cell Line (PLC/PRF/5) or Mouse Splenocytes by Polymer Bound Chlorin e6, Targeted by Galactosamine or Anti-Thy-1.2Antibodies, Respectively
J. Contr. Rel., 25, 71-87 (1993)
 196.  K. Ikesue, P. Kopeckova, J. Kopecek
Degradation of Proteins by Guinea Pig Intestinal Enzymes
Int. J. Pharmaceutics, 95, 171-179 (1993)
 195.  B. Rihova, R.C. Rathi, P. Kopeckova, J. Kopecek
In Vitro Bioadhesion of Carbohydrate-Containing N-(2-Hydroxypropyl)methacrylamide Copolymers to the GI Tract of Guinea Pigs
Int. J. Pharmaceutics, 87, 105-116 (1992)
 194.  C. Konak, P. Kopeckova, J. Kopecek
Photoregulated Association of N-(2-Hydroxypropyl)methacrylamide Copolymers with Azobenzene Containing Side-Chains
Macromolecules, 25, 5451-5456 (1992)
 193.  H. Brøndsted, J. Kopecek
Hydrogels for Site-Specific Drug Delivery to Colon: In Vitro and In Vivo Degradation
Pharmaceutical Res., 9, 1540-1545 (1992)
 192.  J. Kopecek, P. Kopeckova
N-(2-Hydroxypropyl)methacrylamide Copolymers for Colon Specific Drug Delivery
in: Oral Colon-Specific Delivery, D.R. Friend, Ed., CRC Press, Boca Raton, Florida, 1992, pp. 189-211
 191.  P. Kopeckova, K. Ikesue, J. Kopecek
Cleavage of Oligopeptide p-Nitroanilides Attached to N-(2-Hydroxypropyl)methacrylamide Copolymers by Guinea Pig Intestinal Enzymes
Makromol. Chem., 193, 2605-2619 (1992)
 190.  H. Brøndsted, J. Kopecek
pH Sensitive Hydrogels: Characteristics and Potential in Drug Delivery
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 189.  J. Kopecek, P. Kopeckova, H. Brøndsted, R. Rathi, B. Rihova, P.-Y. Yeh, K. Ikesue
Polymers for Colon-Specific Drug Delivery
J. Contr. Rel., 19, 121-130 (1992)
 188.  H.-R. Yen, J.D. Andrade, J. Kopecek
Optically Controlled Ligand Delivery. 3. Photocleavage of 2-Nitrobenzyl Bonds at Solid-Liquid Interface
Polymer, 33, 1763-1767 (1992)
 187.  P. A. Flanagan, R. Duncan, V. Subr, K. Ulbrich, P. Kopeckova, J. Kopecek
Evaluation of Protein - N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates as Targetable Drug-Carriers. 2. Body Distribution of Conjugates Containing Transferrin, Antitransferrin Receptor Antibody or Anti-Thy 1.2 Antibody and Effectiveness of Transferrin-Containing Daunomycin Conjugates against Mouse L1210 Leukaemia In Vivo
J. Contr. Rel., 18, 25-38 (1992)
 186.  M. Singh, R. Rathi, A. Singh, J. Heller, G.P. Talwar, J. Kopecek
Controlled Release of LHRH-DT from Bioerodible Hydrogel Microspheres
Int. J. Pharmaceutics, 76, R5-R8 (1991)
 185.  H.-R. Yen, J.D. Andrade, J. Kopecek
Optically Controlled Ligand Delivery. 2. Copolymers Containing alpha-Methylphenacyl Bonds
J. Appl. Polym. Sci., 43, 1241-1252 (1991)
 184.  R.C. Rathi, P. Kopeckova, B. Rihova, J. Kopecek
N-(2-Hydroxypropyl)methacrylamide Copolymers Containing Pendant Saccharide Moieties. Synthesis and Bioadhesive Properties
J. Polym. Sci., Part A: Polym. Chem., 29, 1895-1902 (1991)
 183.  L. W. Seymour, R. Duncan, V. Chytry, J. Strohalm, K. Ulbrich, J. Kopecek
Intraperitoneal and Subcutaneous Retention of a Soluble Polymeric Drug-Carrier Bearing Galactose
J. Contr. Rel., 16, 255-262 (1991)
 182.  H. Brøndsted, J. Kopecek
Hydrogels for Site-Specific Oral Delivery. Synthesis and Characterization
Biomaterials, 12, 584-592 (1991)
 181.  B. Crepon, J. Jozefonvicz, V. Chytry, B. Rihova, J. Kopecek
Enzymatic Degradation and Immunogenic Properties of Derivatized Dextrans
Biomaterials, 12, 550-554 (1991)
180.  J. Kopecek
Targetable Polymeric Anticancer Drugs: Temporal Control of Drug Activity
Ann. N.Y. Acad. Sci., 618, 335-344 (1991)
 179.  J. Kopecek, B. Rihova, N.L. Krinick
Targetable Photoactivatable Polymeric Drugs
J. Contr. Rel., 16, 137-143 (1991)
 178.  P. Kopeckova, M.A. Longer, J.F. Woodley, R. Duncan, J. Kopecek
Release of p-Nitroaniline from Oligopeptide Side-Chains Attached to N-(2-Hydroxypropyl)methacrylamide Copolymers by Rat Intestinal Brush Border Membrane Enzymes
Makromol. Chem. Rapid Commun., 12, 601-606 (1991)
 177.  Y. Grim, J. Kopecek
Bioadhesive Water-Soluble Polymeric Drug Carriers for Site-Specific Oral Drug Delivery. Synthesis, Characterization and Release of 5-Aminosalicylic Acid by Streptococcum Faecium In Vitro
New Polymeric Mat., 3, 49-59 (1991)
 176.  N.L. Krinick, J. Kopecek
Soluble Polymers as Targetable Drug Carriers
in: Handbook of Experimental Pharmacology, Vol. 100, "Targeted Drug Delivery", R.L. Juliano, Ed., Springer, 1991, pp. 105-179
 175.  M. Pradny, J. Kopecek
Hydrogels for Site-Specific Oral Delivery. Poly[(Acrylic acid)-co-(Butyl Acrylate)] Crosslinked with 4,4'-Di(methacryloylamino)azobenzene
Makromol. Chem., 191, 1887-1897 (1990)
 174.  P. Kopeckova, J. Kopecek
Release of 5-Aminosalicylic Acid from Bioadhesive N-(2-Hydroxypropyl)methacrylamide Copolymers by Azoreductases In Vitro
Makromol. Chem., 191, 2037-2045 (1990)
 173.  V. Subr, R. Duncan, J. Kopecek
Release of Macromolecules and Daunomycin from Hydrophilic Gels Containing Enzymatically Degradable Bonds
J. Biomat. Sci., Polym. Ed., 1, 261-278 (1990)
 172.  N.L. Krinick, B. Rihova, K. Ulbrich, J. Strohalm, J. Kopecek
Targetable Photoactivatable Drugs. 2. Synthesis of N-(2-Hydroxypropyl)methacrylamide Copolymer - Anti-Thy 1.2 Antibodies - Chlorin e6 Conjugates and a Preliminary Study of Their Photodynamic Effect on Mouse Splenocytes In Vitro
Makromol. Chem., 191, 839-856 (1990)
 171.  J.D. Andrade, J.-N. Lin, V. Hlady, J. Herron, D. Christensen, J. Kopecek
Immunosensors: Remaining Problems in the Development of Remote, Continuous, Multi-Channel Devices
in: Biosensor Technology, R.B. Buck et al., Eds., Marcel Dekker, New York 1990, pp. 219-239
 170.  P. Kopeckova, J. Kopecek, J.D. Andrade
The Influence of Poly(Ethylene Oxide) Spacers on the Covalent and Non-Specific Binding of Immunoglobulin G to Silica Surfaces
New Polymeric Mat., 1, 289-297 (1990)
 169.  J.-H. Lee, P. Kopeckova, J. Kopecek, J.D. Andrade
Surface Properties of Copolymers of Alkyl Methacrylates with Methoxy (Polyethylene Oxide) Methacrylates
Biomaterials, 11, 455-464 (1990)
 168.  P.A. Flanagan, R. Duncan, B. Rihova, V. Subr, J. Kopecek
Immunogenicity of Protein - N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates Measured in A/J and B10 Mice
J. Bioact. Comp. Polym., 5, 151-166 (1990)
 167.  L.W. Seymour, K. Ulbrich, J. Strohalm, J. Kopecek, R. Duncan
The Pharmacokinetics of Polymer-Bound Adriamycin
Biochem. Pharmacol., 39, 1125-1131 (1990)
 166.  J. Kopecek
The Potential of Water-Soluble Polymeric Carriers in Targeted and Site-Specific Drug Delivery
J. Contr. Rel., 11, 279-290 (1990)
 165.  J. Cassidy, R. Duncan, G.J. Morrison, J. Strohalm, D. Plocova, J. Kopecek, S.B. Kaye
Activity of N-(2-Hydroxypropyl)methacrylamide Copolymers Containing Daunomycin Against a Rat Tumour Model
Biochem. Pharmacol., 38, 875-879 (1989)
164.  P.A. Flanagan, P. Kopeckova, J. Kopecek, R. Duncan
Evaluation of Protein - N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates as Targetable Drug Carriers. 1. Binding, Pinocytic Uptake and Intracellular Distribution of Transferrin and Anti-Transferrin Receptor Antibody Conjugates
Biochim. Biophys. Acta, 993, 83-91 (1989)
 163.  K.B. O'Hare, I.C. Hume, L. Scarlett, V. Chytry, P. Kopeckova, J. Kopecek, R. Duncan
Effect of Galactose on Interaction of N-(2-Hydroxypropyl)methacrylamide Copolymers with Hepatoma Cells in Culture: Preliminary Application to an Anticancer Agent, Daunomycin
Hepatology 10, 207-214 (1989)
 162.  J.-H. Lee, J. Kopecek, J.D. Andrade
Protein-Resistant Surfaces Prepared by PEO-Containing Block Copolymer Surfactants
J. Biomed. Mater. Res., 23, 351-368 (1989)
 161.  M.V. Solovskij, K. Ulbrich, O.V. Nazarova, N.V. Zubko, E.F. Panarin, J. Kopecek
Investigation of the Aminolysis of p-Nitrophenyl Esters of N-(Meth)acryloylaminophenoxyacetic Acids and Their Copolymers with N-(2-Hydroxypropyl)methacrylamide by 6-Aminopenicillanic Acid
Makromol. Chem., 190, 2245-2254 (1989)
 160.  B. Rihova, M. Bilej, V. Vetvicka, K. Ulbrich, J. Strohalm, J. Kopecek, R. Duncan
Biocompatibility of N-(2-Hydroxypropyl)methacrylamide Copolymers Containing Adriamycin
Biomaterials 10, 335-342 (1989)
 159.  B. Rihova, V. Veres, L. Fornusek, K. Ulbrich, J. Strohalm, V. Vetvicka, M. Bilej, J. Kopecek
Action of Polymeric Prodrugs Based on N-(2-Hydroxypropyl)methacrylamide Copolymers. 2. Body Distribution and T-Cell Accumulation of Free and Polymer Bound [125I]Daunomycin
J. Contr. Rel., 10, 37-49 (1989)
 158.  B. Rihova, V. Vetvicka, J. Strohalm, K. Ulbrich, J. Kopecek
Action of Polymeric Prodrugs Based on N-(2-Hydroxypropyl)methacrylamide Copolymers. 1. Suppression of the Antibody Response and Proliferation of Mouse Splenocytes In Vivo
J. Contr. Rel., 9, 21-32 (1989)
157.  R. Duncan, I.C. Hume, P. Kopeckova, K. Ulbrich, J. Strohalm, J. Kopecek
Anticancer Agents Coupled to N-(2-Hydroxypropyl)methacylamide Copolymers. 3. Evaluation of Adriamycin Conjugates Against Mouse Leukaemia L1210 In Vivo
J. Contr. Rel.,10, 51-63 (1989)
 156.  B.K. Armstrong, Q. Smith, S.I. Rapoport, J. Strohalm, J. Kopecek, R. Duncan
Osmotic Opening of the Blood-Brain Barrier Permeability to N-(2-Hydroxypropyl)methacrylamide Copolymers. Effect of Polymer Mw, Charge and Hydrophobicity
J. Contr. Rel., 10, 27-35 (1989)
 155.  R. Duncan, L.W. Seymour, K. Ulbrich, J. Kopecek
Soluble Synthetic Polymers for Targeting and Controlled Release of Anticancer Agents, Particularly Anthracycline Antibiotics
J. Bioact. Comp. Polym., 3, 4-15 (1988)
 154.  N.L. Krinick, B. Rihova, K. Ulbrich, J.D. Andrade, J. Kopecek
Targetable Photoactivatable Drugs. 1. Synthesis of Water-Soluble Galactosamine Containing Polymeric Carriers of Chlorin e6 and Their Photodynamic Effect on PLC Cells In Vitro
Proc. SPIE, 997, 70-83 (1988)
 153.  V. Subr, J. Kopecek, J. Pohl, M. Baudys, V. Kostka
Cleavage of Oligopeptide Side-Chains in N-(2-Hydroxypropyl)methacrylamide Copolymers by Mixtures of Lysosomal Enzymes
J. Contr. Rel., 9, 133-140 (1988)
 152.  J.D. Andrade, J. Herron, J.-N. Lin, H.-R. Yen, J. Kopecek, P. Kopeckova
On-Line Sensors for Coagulation Proteins: Concept and Progress Report
Biomaterials, 9, 76-79 (1988)
 151.  H.-R. Yen, J. Kopecek, J.D. Andrade
Optically Controlled Ligand Delivery. 1. Synthesis of Water-Soluble Copolymers Containing Photocleavable Bonds
Makromol. Chem., 190, 69-82 (1989)
 150.  J. Kopecek
Development of Tailor-Made Polymeric Prodrugs for Systemic and Oral Delivery
J. Bioact. Comp. Polym., 3, 16-26 (1988)
 149.  J.F. Bridges, J.F. Woodley, R. Duncan, J. Kopecek
Soluble N-(2-Hydroxypropyl)methacrylamide Copolymers as a Potential Oral, Controlled Release, Drug Delivery System. 1. Bioadhesion to the Intestinal Surface In Vitro
Int. J. Pharmaceutics, 44, 213-223 (1988)
 148.  B. Rihova, P. Kopeckova, J. Strohalm, P. Rossmann, V. Vetvicka, J. Kopecek
Antibody Directed Affinity Therapy Applied to the Immune System: In Vivo Effectiveness and Limited Toxicity of Daunomycin Conjugates to HPMA Copolymers and Targeting Antibody
Clin. Immunol. Immunopathol., 46, 100-114 (1988)
 147.  R. Duncan, P. Kopeckova, J. Strohalm, I.C. Hume, J.B. Lloyd, J. Kopecek
Anticancer Agents Coupled to N-(2-Hydroxypropyl)methacrylamide Copolymers. 2. Evaluation of Daunomycin Conjugates In Vivo against L1210 Leukaemia
Brit. J. Cancer, 57, 147-156 (1988)
 146.  H. Braselmann, D. Kirstein, J. Vacik, J. Kopecek
The Role of Water at the Permeation of Non-electrolytes Through Hydrophilic Membranes
Acta Polymerica, 38, 196-199 (1987)
 145.  J. Kopecek, R. Duncan
Targetable Polymeric Prodrugs
J. Contr. Rel., 6, 315-327 (1987)
 144.  K. Ulbrich, C. Konak, Z. Tuzar, J. Kopecek
Solution Properties of Drug Carriers Based on Poly[N-(2-Hydroxypropyl)methacrylamide] Containing Biodegradable Bonds
Makromol. Chem., 188, 1261-1272 (1987)
 143.  V. Chytry, J. Kopecek, E. Leibnitz, K. O'Hare, L. Scarlett, R. Duncan
Copolymers of 6-O-Methacryloyl-D-Galactose and N-(2-Hydroxypropyl)methacrylamide: Targeting to Liver after Intravenous Administration to Rats
New Polymeric Mat., 1, 21-28 (1987)
 142.  K. Ulbrich, E.I. Zacharieva, J. Kopecek, I.C. Hume, R. Duncan
Polymer-Bound Derivatives of Sarcolysin and their Antitumor Activity against Mouse and Human Leukemia In Vitro
Makromol. Chem., 188, 2497-2509 (1987)
 141.  L.W. Seymour, R. Duncan, P. Kopeckova, J. Kopecek
Potential of Sugar Residues Attached to N-(2-Hydroxypropyl)methacrylamide Copolymers as Targeting Groups for the Selective Delivery of Drugs
J. Bioact. Comp. Polym., 2, 97-119 (1987)
 140.  L.W. Seymour, R. Duncan, J. Strohalm, J. Kopecek
Effect of Molecular Weight of N-(2-Hydroxypropyl)methacrylamide Copolymers on Body Distribution and Rate of Excretion after Subcutaneous, Intraperitoneal and Intravenous Administration to Rats
J. Biomed. Mater. Res., 21, 1341-1358 (1987)
 139.  L.W. Seymour, R. Duncan, P. Kopeckova, J. Kopecek
Daunomycin - and Adriamycin - N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates. Toxicity Reduction by Improved Drug Delivery
Cancer Treat. Rev., 14, 319-327 (1987)
 138.  J. Kopecek, R. Duncan
Poly[N-(2-Hydroxypropyl)methacrylamide] Macromolecules as Drug Carrier Systems
in: Polymers in Controlled Drug Delivery, L. Illum, S.S. Davis, Eds., Wright, Bristol, U.K., pp. 152-170 (1987)
 137.  R. Duncan, P. Kopeckova-Rejmanova, J. Strohalm, I. Hume, H.C. Cable, J. Pohl, J.B. Lloyd, J. Kopecek
Anticancer Agents Coupled to N-(2-Hydroxypropyl)methacrylamide Copolymers. 1. Evaluation of Daunomycin and Puromycin Conjugates In Vitro
Brit. J. Cancer, 55, 165-174 (1987)
 136.  S.A. Cartlidge, R. Duncan, J.B. Lloyd, P. Kopeckova-Rejmanova, J. Kopecek
Soluble, Crosslinked N-(2-Hydroxypropyl)methacrylamide Copolymers as Potential Drug Carriers. 3. Targeting by Incorporation of Galactosamine Residues. Effect of Route of Administration
J. Contr. Rel., 4, 265-278 (1987)
 135.  S.A. Cartlidge, R. Duncan, J.B. Lloyd, P. Kopeckova-Rejmanova, J. Kopecek
Soluble Crosslinked N-(2-Hydroxypropyl)methacrylamide Copolymers as Potential Drug Carriers. 2. Effect of Molecular Weight on Blood Clearance and Body Distribution in the Rat after Intravenous Administration. Distribution of Unfractionated Copolymer after Intraperitoneal, Subcutaneous or Oral Administration
J. Contr. Rel., 4, 253-264 (1987)
 134.  R. Duncan, H.C. Cable, J. Strohalm, J. Kopecek
Pinocytic Capture and Endocytosis of Rat Immunoglobulin IgG - N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates by Rat Visceral Yolk Sacs Cultured In Vitro
Biosci. Rep., 6, 869-878 (1986)
 133.  H. Tlaskalova-Hogenova, J. Coupek, A. Frydrychova, V. Vetvicka, J. Kopecek, M. Pospisil, H. Fiebig, L. Fornusek, J. Brochier, L. Prokesova, P. Mancal
Separation of Human Lymphoid Cells by Affinity Chromatography and Cell Surface Labelling by Poly(2-Hydroxyethylmethacrylate) Particles Using Monoclonal Antibodies
J. Chromatogr. Biomed. Appl., 376, 401-408 (1986)
 132.  E. Paluska, A. Hruba, O. Sterba, J. Kopecek
Effect of a Synthetic Poly[N-(2-Hydroxypropyl)methacrylamide] (Duxon) on Haemopoiesis and Graft versus Host Reaction
Folia Biologica (Prague), 32, 91-102 (1986)
131.  V. Subr, J. Kopecek, R. Duncan
Degradation of Oligopeptide Sequences Connecting Poly[N-(2-Hydroxypropyl)methacrylamide] Chains by Lysosomal Cysteine Proteinases
J. Bioact. Comp. Polym., 1, 133-146 (1986)
 130.  J. Simeckova, D. Plocova, B. Rihova, J. Kopecek
Activity of Complement in the Presence of N-(2-Hydroxypropyl)methacrylamide Copolymers
J. Bioact. Comp. Polym., 1, 20-31 (1986)
 129.  J.B. Lloyd, R. Duncan, J. Kopecek
Synthetic Polymers as Carriers for Chemotherapeutic Agents
Biochem. Soc. Trans., 14, 391-392 (1986)
 128.  V. Vetvicka, L. Fornusek, P.W. Kincade, J. Kopecek
Co-Expression of Different Types of Fc Receptors on Murine Peritoneal Macrophages
Eur. J. Immunol., 16, 901-905 (1986)
 127.  L.A. McCormick, L.C.W. Seymour, R. Duncan, J. Kopecek
Interaction of a Cationic N-(2-Hydroxypropyl)methacrylamide Copolymer with Rat Visceral Yolk Sac Cultured In Vitro and Rat Liver In Vivo
J. Bioact. Comp. Polym., 1, 4-19 (1986)
 126.  B. Rihova, J. Kopecek, P. Kopeckova-Rejmanova, J. Strohalm, D. Plocova, H. Semoradova
Bioaffinity Therapy with Antibodies and Drugs Bound to Soluble Synthetic Polymers
J. Chromatogr. Biomed. Appl., 376, 221-233 (1986)
 125.  R. Duncan, L.C.W. Seymour, L. Scarlett, J.B. Lloyd, P. Rejmanova, J. Kopecek
Fate of N-(2-Hydroxypropyl)methacrylamide Copolymers with Pendent Galactosamine Residues after Intravenous Administration to Rats
Biochim. Biophys. Acta, 880, 62-71 (1986)
 124.  V. Subr, R. Duncan, K. Hanada, H.C. Cable, J. Kopecek
A Lysosomotropic Polymeric Inhibitor of Cysteine Proteinases
J. Contr. Rel., 4, 63-68 (1986)
 123.  S.A. Cartlidge, R. Duncan, J.B. Lloyd, P. Rejmanova, J. Kopecek
Soluble Crosslinked N-(2-Hydroxypropyl)methacrylamide Copolymers as Potential Drug Carriers. 1. Pinocytosis by Rat Visceral Yolk Sacs and Rat Intestine Cultured In Vitro. Effect of Molecular Weight on Uptake and Intracellular Degradation
J. Contr. Rel., 3, 55-66 (1986)
 122.  K. Ulbrich, J. Strohalm, J. Kopecek
Poly(Ethylene Glycol)s Containing Enzymatically Degradable Bonds
Makromol. Chem., 187, 1131-1144 (1986)
 121.  H. Tlaskalova-Hogenova, J. Kopecek, K. Ulbrich, F. Rypacek, J. Pospisil
In Vivo and In Vitro Immunogenicity of Water-Soluble Haptenated Copolymers for Mouse and Human Lymphocytes
Makromol. Chem., Suppl. 9, 137-143 (1985)
 120.  B. Rihova, J. Kopecek
Biological Properties of Targetable Poly[N-(2-Hydroxypropyl)methacrylamide] - Antibody Conjugates
J. Contr. Rel., 2, 289-310 (1985)
 119.  R. Rihova, J. Kopecek, K. Ulbrich, V. Chytry
Immunogenicity of N-(2-Hydroxypropyl)methacrylamide Copolymers
Makromol. Chem., Suppl. 9, 13-24 (1985)
 118.  J. Kopecek
Polymers with Controlled Biodegradability as Carriers of Biologically Active Compounds (in Russian)
Zhur. Khim. Obsh., 30, 372-378 (1985)
 117.  L. Fornusek, V. Vetvicka, J. Zidkova, J. Kopecek
Hydrophilic Polymeric Microspheres: Their Use in Immunological Methods
Makromol. Chem. Suppl., 9, 125-127 (1985)
 116.  J. Kopecek, R. Rejmanova, R. Duncan, J.B. Lloyd
Controlled Release of Drug Model from N-(2-Hydroxypropyl)methacrylamide Copolymers
Ann N.Y. Acad. Sci., 446, 93-104 (1985)
 115.  J.B. Lloyd, R. Duncan, J. Kopecek, P. Rejmanova
Targeting and Lysosomal Handling of Polymethacrylamide - Oligopeptide Conjugates
in: Receptor-Mediated Targeting of Drugs, G. Gregoriadis, G. Poste, J. Senior, A. Trouet, Eds., Plenum Press, New York, pp. 417-425, (1985)
 114.  R. Duncan, J.B. Lloyd, P. Rejmanova, J. Kopecek
Methods of Targeting N-(2-Hydroxypropyl)methacrylamide Copolymers to Particular Cell Types
Makromol. Chem., Suppl. 9, 3-12 (1985)
 113.  A. Laane, A. Aaviksaar, M. Haga, V. Chytry, J. Kopecek
Preparation of Polymer-Modified Enzymes of Prolonged Circulation Times. Poly[N-(2-Hydroxypropyl)methacrylamide] Bound Acetylcholinesterase
Makromol. Chem., Suppl. 9, 35-42 (1985)
 112.  P. Rejmanova, J. Kopecek, R. Duncan, J.B. Lloyd
Stability in Rat Plasma and Serum of Lysosomally Degradable Oligopeptide Sequences in N-(2-Hydroxypropyl)methacrylamide Copolymers
Biomaterials, 6, 45-48 (1985)
 111.  D. Kirstein, H. Braselman, J. Vacik, J. Kopecek
Influence of Medium and Matrix Composition on Diffusivities in Charged Membranes
Biotechnol. Bioeng., 27, 1382-1384 (1985)
 110.  V. Vetvicka, L. Fornusek, B. Rihova, J. Kopecek
Properties of Macrophages from Low and High Responder Strains of Mice. 1. Effect of Antigen Stimulus
Folia Biologica (Prague), 31, 20-33 (1985)
 109.  V. Vetvicka, L. Fornusek, M. Holub, J. Zidkova, J. Kopecek
Macrophages of Athymic Nude Mice: Fc Receptors, C Receptors, Phagocytic and Pinocytic Activities
Eur. J. Cell. Biol., 35, 35-40 (1984)
 108. S.A. Cartlidge, P. Rejmanova, R. Duncan, J. Kopecek, J.B. Lloyd
Targeting of Soluble Crosslinked N-(2-Hydroxypropyl)methacrylamide Copolymers In Vivo. A Potential Drug Delivery System
Biochem. Soc. Trans., 12, 1064-1065 (1984) 
 107. R. Duncan, H.C. Cable, P. Rejmanova, J. Kopecek, J.B. Lloyd
Tyrosinamide Residues Enhance Pinocytic Capture of N-(2-Hydroxypropyl)methacrylamide Copolymers
Biochim. Biophys. Acta, 799, 1-8 (1984) 
 106. B. Rihova, J. Kopecek, K. Ulbrich, J. Pospisil, P. Mancal
Effect of the Chemical Structure of N-(2-Hydroxypropyl)methacrylamide Copolymers on their Ability to Induce Antibody Formation in Inbred Strains of Mice
Biomaterials, 5, 143-148 (1984) 
 105. J. Pato, M. Azori, K. Ulbrich, J. Kopecek
Polymers Containing Enzymatically Degradable Bonds. 9. Chymotrypsin Catalyzed Hydrolysis of p-Nitroanilide Drug Model Bound via Oligopeptides onto Poly(Vinylpyrrolidone-co-Maleic Anhydride)
Makromol. Chem., 185, 231-237 (1984) 
 104. J.B. Lloyd, R. Duncan, J. Kopecek
Synthetic Polymers as Targetable Carriers for Drugs
Pure Appl. Chem., 56, 1301-1304 (1984) 
 103. R. Duncan, J. Kopecek, J.B. Lloyd
Drug Targeting to Lysosomes
Biochem. Soc. Trans., 12, 913-915 (1984) 
 102. J. Kopecek
Controlled Biodegradability of Polymers - a Key to Drug Delivery Systems
Biomaterials, 5, 19-25 (1984) 
 101. J. Kopecek
Synthesis of Tailor-Made Soluble Polymeric Drug Carriers
in: Recent Advances in Drug Delivery Systems, J.M. Anderson, S.W. Kim, Eds., Plenum Press, New York, pp. 41-62, (1984) 
 100. R. Duncan, J. Kopecek
Soluble Synthetic Polymers as Potential Drug Carriers
Adv. Polym. Sci., 57, 51-101 (1984) 
 99. L. Fornusek, J. Kopecek, V. Vetvicka
An Advantageous Method for Detection of Fc-Receptors and for Studying Fc-Receptor Mediated Phagocytosis
Immunology Letters, 7, 29-33 (1983) 
 98. V. Vetvicka, L. Fornusek, J. Kopecek, D. Prikrylova
Phagocytosis of 2-Hydroxyethylmethacrylate Copolymer Particles by Different Types of Macrophages
Folia Biologica (Prague), 29, 424-428 (1983)
 97. P. Rejmanova, J. Pohl, M. Baudys, V. Kostka, J. Kopecek
Polymers Containing Enzymatically Degradable Bonds. 8. Degradation of Oligopeptide Sequences in N-(2-Hydroxypropyl)methacrylamide Copolymers by Bovine Spleen Cathepsin B
Makromol. Chem., 184, 2009-2020 (1983) 
 96. R. Duncan, J. Kopecek, P. Rejmanova, J.B. Lloyd
Targeting of N-(2-Hydroxypropyl)methacrylamide Copolymers to Liver by Incorporation of Galactose Residues
Biochim. Biophys. Acta, 755, 518-521 (1983)
 95. R. Duncan, J. Kopecek, J.B. Lloyd
Development of N-(2-Hydroxypropyl)methacrylamide Copolymers as Carriers of Therapeutic Agents
in: Polymers in Medicine: Biomedical and Pharmacological Applications, E. Chiellini, P. Giusti, Eds., Plenum Press, New York, pp. 97-113, (1983) 
 94. J. Kopecek, K. Ulbrich
Biodegradation of Biomedical Polymers
Progr. Polym. Sci., 9, 1-58 (1983) 
 93. J. Kopecek, P. Rejmanova
Enzymatically Degradable Bonds in Synthetic Polymers
in: Controlled Drug Delivery, S.D. Bruck, Ed., CRC Press, Boca Raton, Florida, Vol. I, pp. 81-124, (1983) 
 92. V. Chytry, J. Kopecek
Activation of Poly[N-(2-Hydroxypropyl)methacrylamide] for Binding of Bioactive Molecules. 2. Activation with Cyanogen Bromide
Makromol. Chem., 184, 1345-1353 (1983) 
 91. A. Laane, M. Haga, A. Aaviksaar, V. Chytry, J. Kopecek
Activation of Poly[N-(2-Hydroxypropyl)methacrylamide] for Binding of Bioactive Molecules. 1. Activation with 4-Nitrophenyl Chloroformate
Makromol. Chem., 184, 1339-1344 (1983) 
 90. B. Rihova, K. Ulbrich, J. Kopecek, P. Mancal
Immunogenicity of N-(2-Hydroxypropyl)methacrylamide Copolymers - Potential Hapten or Drug Carriers
Folia microbiologica (Prague), 28, 217-227 (1983) 
 89. R. Duncan, H.C. Cable, J.B. Lloyd, P. Rejmanova, J. Kopecek
Polymers Containing Enzymatically Degradable Bonds. 7. Design of Oligopeptide Side-Chains in Poly[N-(2-Hydroxypropyl)methacrylamide] Copolymers to Promote Efficient Degradation by Lysosomal Enzymes
Makromol. Chem., 184, 1997-2008 (1983) 
 88. M.V. Solovskij, K. Ulbrich, J. Kopecek
Synthesis of N-(2-Hydroxypropyl)methacrylamide Copolymers with Antimicrobial Activity
Biomaterials, 4, 44-48 (1983) 
 87. R. Duncan, H.C. Cable, J.B. Lloyd, P. Rejmanova, J. Kopecek
Degradation of Side-Chains of N-(2-Hydroxypropyl)methacrylamide Copolymers by Lysosomal Thiol Proteinases
Biosci. Rep., 2, 1041-1046 (1982) 
 86. V. Vetvicka, L. Fornusek, J. Kopecek, J. Kaminkova, L. Kasparek, M. Vranova
Phagocytosis of Human Blood Leukocytes: A Simple Micromethod
Immunology Letters, 5, 97-100 (1982) 
 85. K. Ulbrich, J. Strohalm, J. Kopecek
Polymers Containing Enzymatically Degradable Bonds. 6. Hydrophilic Gels Cleavable by Chymotrypsin
Biomaterials, 3, 150-154 (1982) 
 84. V. Chytry, J. Kopecek, P. Sikk, R. Sinijarv, A. Aaviksaar
A Convenient Model System for the Study of the Influence of Water-Soluble Polymer Carrier on the Interaction Between Proteins
Makromol. Chem. Rapid Commun., 3, 11-15 (1982) 
 83. J. Kopecek
Biodegradation of Polymers for Biomedical Use
in: IUPAC Macromolecules, H. Benoit, P. Rempp. Eds., Pergamon Press, Oxford, pp. 305-320, (1982) 
 82. R. Duncan, P. Rejmanova, J. Kopecek, J.B. Lloyd
Pinocytic Uptake and Intracellular Degradation of N-(2-Hydroxypropyl)methacrylamide) Copolymers. A Potential Drug Delivery System
Biochim. Biophys. Acta, 678, 143-150 (1981) 
 81. L. Fornusek, V. Vetvicka, J. Kopecek
Difference in Phagocytic Activity of Methacrylate Copolymer Particles in Normal and Stimulated Macrophages
Experientia, 37, 418-420 (1981) 
 80. J. Hrouz, M. Ilavsky, K. Ulbich, J. Kopecek
The Photoelastic Behaviour of Dry and Swollen Networks of Poly(N,N-Diethylacrylamide) and of its Copolymers with N-tert. Butylacrylamide
Europ. Polym. J., 17, 361-366 (1981) 
 79.  J. Kopecek, I. Cifkova, P. Rejmanova, J. Strohalm, B. Obereigner, K. Ulbrich
Polymers Containing Enzymatically Degradable Bonds. 4. Preliminary Experiments In Vivo
Makromol. Chem., 182, 2941-2949 (1981)
 78. K. Ulbrich, J. Strohalm, J. Kopecek
Polymers Containing Enzymatically Degradable Bonds. 3. Poly[N-(2-Hydroxypropyl)-methacrylamide] Chains Connected by Oligopeptide Sequences Cleavable by Trypsin
Makromol. Chem., 182, 1917-1928 (1981) 
 77. P. Rejmanova, B. Obereigner, J. Kopecek
Polymers Containing Enzymatically Degradable Bonds. 2. Poly[N-(2-Hydroxypropyl)methacrylamide] Chains Connected by Oligopeptide Sequences Cleavable by Chymotrypsin
Makromol. Chem., 182, 1899-1915 (1981) 
 76. J. Kopecek, P. Rejmanova, V. Chytry
Polymers Containing Enzymatically Degradable Bonds 1. Chymotrypsin Catalyzed Hydrolysis of p-Nitroanilides of Phenylalanine and Tyrosine Attached to Side-Chains of Copolymers of N-(2-Hydroxypropyl)methacrylamide
Makromol. Chem., 182, 799-809 (1981) 
 75. J. Kopecek
Hydrophilic Biomedical Polymers (in Bulgarian)
Chimija i Industrija, 224-227 (1981) 
 74. J. Kopecek
Soluble Polymers in Medicine
in: Systemic Aspects of Biocompatibility, D.F. Williams, Ed., CRC Press, Boca Raton, Florida, Vol. II, pp. 159-180 (1981) 
 73. A. Laane, V. Chytry, M. Haga, P. Sikk, A. Aaviksaar, J. Kopecek
Covalent Attachment of Chymotrypsin to Poly[N-(2-Hydroxypropyl)methacrylamide]
Collection Czechoslov. Chem. Commun., 46, 1466-1473 (1981) 
 72. J. Cinatl, O. Sterba, E. Paluska, V. Polednova, J. Kopecek
New Types of Synthetic Infusion Solutions. The Effects of Duxon on the Cell Proliferation In Vitro (in Czech)
Cs. farmacie, 29, 134-138 (1980) 
 71. O. Sterba, Z. Uhlirova, R. Petz, L. Viktora, A. Jirasek, J. Kopecek
Experimental Contribution to the Biological Evaluation of the Czechoslovak Infusion Solution (in Czech)
Cas. lek. ceskych, 119, 994-997 (1980) 
 70. R. Duncan, J.B. Lloyd, J. Kopecek
Degradation of Side Chains of N-(2-Hydroxypropyl)methacrylamide Copolymers by Lysosomal Enzymes
Biochem. Biophys. Res. Commun., 94, 284-290 (1980) 
 69. K. Ulbrich, E.I. Zacharieva, B. Obereigner, J. Kopecek
Polymers Containing Enzymatically Degradable Bonds. 5. Hydrophilic Polymers Degradable by Papain
Biomaterials, 1, 199-204 (1980) 
 68. E. Paluska, J. Cinatl, L. Korcakova, O. Sterba, J. Kopecek, A. Hruba, J. Nezvalova, R. Stanek
Immunosuppressive Effect of a Synthetic Polymer - Poly[N-(2-Hydroxypropyl)methacrylamide] (Duxon)
Folia Biologica (Prague), 26, 304-311 (1980) 
 67. V. Kudela, J. Vacik, J. Kopecek
Strong Acid Membranes with Enhanced Hydrophilicity
J. Membrane Sci., 6, 123-131 (1980) 
 66. H. Braselman, J. Vacik, J. Kopecek, D. Kirstein
Regulation of Transport in Artificial Membranes by Environmental Hydrogen-Ion Concentration
Europ. Polym. J., 16, 431-435 (1980) 
 65. V. Vetvicka, V. Viklicky, L. Jaroskova, J. Kopecek
Comparison of the Functional Activity of Normal and Stimulated Peritoneal Exudate Cells in Suspension and After Adherence to the Substrate
Folia Biologica (Prague), 25, 403-404 (1979) 
 64. J. Vacik, L.K. Satajeva, G.V. Samsonov, J. Kalal, J. Kopecek
Porous Copolymers of Methacrylic Acid with N-(2-Hydroxypropyl)methacrylamide and with 2-Hydroxyethyl Methacrylate. Study of Sorption Properties
Collection Czechoslov. Chem. Commun., 44, 1931-1941 (1979) 
 63. J. Vacik, Z. Pelzbauer, N.N. Kuznetsova K.P. Papukova, L.K. Satajeva, G.V. Samsonov, J. Kalal, J. Kopecek
Porous Copolymers of Methacrylic Acid with N-(2-Hydroxypropyl)methacrylamide and with 2-Hydroxyethyl Methacrylate. Preparation, Swelling and Morphology
Collection Czechoslov. Chem. Commun., 44, 1925-1930 (1979) 
 62. L.K. Satajeva, G.V. Samsonov, J. Vacik, J. Kopecek, J. Kalal
Permeability of Heterogeneous Membranes Based on Methacrylic Acid
J. Appl. Polym. Sci., 23, 2245-2251 (1979) 
 61. J. Kopecek, P. Rejmanova
Reactive Copolymers of N-(2-Hydroxypropyl)methacrylamide with N-Methacryloylated Derivatives of L-Leucine and L-Phenylalanine. II. Reaction with the Polymeric Amine and Stability of Crosslinks Towards Chymotrypsin In Vitro
J. Polym. Sci., Polym. Symp., 66, 15-32 (1979) 
 60. K. Ulbrich, J. Kopecek
Crosslinked Copolymers of N,N-Diethylacrylamide with Improved Mechanical Properties
J. Polym. Sci., Polym. Symp., 66, 209-219 (1979) 
 59. B. Obereigner, M. Buresova, A. Vrana, J. Kopecek
Preparation of Polymerizable Derivatives of N-(4-Aminobenzenesulfonyl)-N'-Butylurea
J. Polym. Sci., Polym. Symp., 66, 41-52 (1979) 
 58. M. Ilavsky, K. Dusek, J. Vacik, J. Kopecek
Deformational, Swelling and Potentiometric Behaviour of Ionized Gels of 2-Hydroxyethyl Methacrylate - Methacrylic Acid Copolymers
J. Appl. Polym. Sci., 23, 2073-2082 (1979) 
 57. J. Kalal, L. Sprincl, J. Kopecek, T.E. Lipatova, E.V. Lebedev, N.I. Dovgopol
Supermolecular Structure of Hydrophilic Polymers Based on Poly(Glycol Methacrylates) Contacted with the Organism's Tissue (in Russian)
Vysokomol. Soed. B, 20, 751-755 (1978) 
 56. J. Vacik, K. Ulbrich, J. Exner, J. Kopecek
Permeability of Hydrophilic Membranes Based on Poly[N-Substituted (Meth)acrylamides]
Collection Czechoslov. Chem. Commun., 43, 1221-1226 (1978) 
 55. J. Strohalm, J. Kopecek
Poly[N-(2-Hydroxypropyl)methacrylamide]. IV. Heterogeneous Polymerization
Angew. Makromol. Chem., 70, 109-118 (1978) 
 54. J. Kalal, J. Drobnik, J. Kopecek, J. Exner
Synthetic Polymers in Chemotherapy: General Problems
in: Polymeric Drugs, L.G. Donaruma, O. Vogl, Eds., Academic Press, New York, pp. 131-159 (1978) 
 53. J. Kalal, J. Drobnik, J. Kopecek, J. Exner
Soluble Polymers for Medicine
Brit. Polym. J., 10, 111-114 (1978) 
 52. K. Ulbrich, K. Dusek, M. Ilavsky, J. Kopecek
Preparation and Properties of Poly(N-Butylmethacrylamide) Networks
Europ. Polym. J., 14, 45-49 (1978) 
 51. V. Chytry, A. Vrana, J. Kopecek
Synthesis and Activity of a Polymer which Contains Insulin Covalently Bound on a Copolymer of N-(2-Hydroxypropyl)methacrylamide and N-Methacryloylglycylglycine 4-Nitrophenyl Ester
Makromol. Chem., 179, 329-336 (1978) 
 50. K. Ulbrich, M. Ilavsky, B. Obereigner, J. Kopecek
Preparation and Properties of Poly(2,4-Pentadiene-1-ol)
Angew. Makromol. Chem., 67, 137-149 (1978) 
 49. V. Kudela, J. Vacik, J. Kopecek
pH-Dependent Electrochemical Behaviour of Hydrophilic Ampholytic Membranes
Europ. Polym. J.,13, 811-813 (1977) 
 48. O. Benesova, L. Sprincl, K. Ulbrich, B. Obereigner, J. Drobnik, J. Kalal, J. Kopecek
Biological Effects of 2,4-Pentadiene-1-ol
Chem. Biol. Interactions, 18, 111-117 (1977) 
 47. J. Kopecek
Reactive Copolymers of N-(2-Hydroxypropyl)methacrylamide with N-Methacryloylated Derivatives of L-Leucine and L-Phenylalanine. I. Preparation, Characterization and Reaction with Diamines
Makromol. Chem., 178, 2169-2183 (1977) 
 46. J. Vacik, M. Czakova, J. Exner, J. Kalal, J. Kopecek
Permeability of Metabolites Through Hydrophilic Membranes
Collection Czechoslov. Chem. Commun., 42, 2786-2790 (1977) 
 45. K. Ulbrich, L. Cech, J. Kalal, J. Kopecek
Polymerization Kinetics of N,N-Diethylacrylamide
Collection Czechoslov. Chem. Commun., 42, 2666-2671 (1977) 
 44. K. Ulbrich, M. Ilavsky, K. Dusek, J. Kopecek
Preparation and Properties of Poly(N-Ethylmethacrylamide) Networks
Europ. Polym. J., 13, 579-585 (1977) 
 43. J Kopecek
Soluble Biomedical Polymers
Polymers in Medicine (Wroclaw), 7, 191-221 (1977) 
 42. P. Rejmanova, J. Labsky, J. Kopecek
Aminolyses of Monomeric and Polymeric p-Nitrophenyl Esters of Methacryloylated Amino Acids
Makromol. Chem., 178, 2159-2168 (1977) 
 41. L. Sprincl, J. Exner, O. Sterba, J. Kopecek
New Types of Synthetic Infusion Solutions. III. Elimination and Retention of Poly[N-(2-Hydroxypropyl)methacrylamide] in a Test Organism
J. Biomed. Mater. Res., 10, 953-963 (1976) 
 40. L. Korcakova, E. Paluska, V. Haskova, J. Kopecek
A Simple Test for Immunogenicity of Colloidal Infusion Solutions - the Draining Lymph Node Activation
Z. Immun. Forsch., 151, 219-223 (1976) 
 39. L. Sprincl, T. Terescenko, J. Kalal, T.E. Lipatova, J. Kopecek, G.A. Pchakadze
Mucopolysaccharide Complexes in the Fibrous Tissue Surrounding Hydrophilic Polymers in Subcutaneous Implantation
Polymers in Medicine (Wroclaw), 6, 185-190 (1976) 
 38. T.E. Lipatova, G.A. Pchakadze, T.L. Terescenko, J. Kalal, L. Sprincl, J. Kopecek
Comparative Characteristics of Polyurethanes and Hydrophilic Polymers Based on Poly(Glycol Methacrylates) Used as Alloplastics (in Ukrainian)
Izv. Ukr. Acad. Sci., 3, 33-45 (1976) 
 37. J. Drobnik, J. Kopecek, J. Labsky, P. Rejmanova, J. Exner, V. Saudek, J. Kalal
Enzymatic Cleavage of Side-Chains of Synthetic Water-Soluble Polymers
Makromol. Chem., 177, 2833-2848 (1976) 
 36. K. Ulbrich, J. Kopecek
Polymerization Kinetics of N-Ethylacrylamide
Collection Czechoslov. Chem. Commun., 41, 61-66 (1976) 
 35. K. Ulbrich, J. Kopecek
Radical Polymerization of N-Substituted Methacrylamides
Europ. Polym. J., 12, 183-187 (1976) 
 34. T.E. Lipatova, G.A. Pchakadze, T.L. Terescenko, L. Sprincl, J. Kalal, J. Kopecek
New Types of Polyurethane Tissue Adhesives and Their Application in Surgery (In Czech)
Voj. zdrav. listy, 45, 25-29 (1976) 
 33. J. Strohalm, K. Ulbrich, J. Exner, J. Kopecek
Copolymerization of N-Ethylacrylamide with N-Monosubstituted Methacrylamides
Angew. Makromol. Chem., 49, 83-92 (1976) 
 32. J. Janacek, J. Kolarik, J. Vacik, J. Kopecek
Mechanical Responses of 2-Hydroxyethyl Methacrylate - Methacrylonitrile and 2-Hydroxyethyl Methacrylate - Acrylonitrile Copolymer Networks
Intern. J. Polym. Mater., 5, 59-70 (1976) 
 31. J. Kolarik, J. Kopecek, J. Vacik, J. Janacek
Relaxation Behaviour of Poly(N-Monosubstituted Methacrylamides)
Intern. J. Polym. Mater., 5, 89-97 (1976) 
 30. O. Sterba, E. Paluska, O. Jozova, J. Spunda, J. Nezvalova, L. Sprincl, J. Kopecek, J. Cinatl
New Types of Synthetic Infusion Solutions. II. Basic Biological Properties of Poly[N-(2-Hydroxypropyl)methacrylamide] (in Czech)
Cas. lek. ceskych, 114, 1268-1270 (1975) 
 29. J. Vacik, J. Kopecek
Specific Resistances of Hydrophilic Membranes Containing Ionogenic Groups
J. Appl. Polym. Sci., 19, 3029-3044 (1975) 
 28. S. Luby, E. Sumbalova, J. Kopecek
Adjusting of Thin Layer Resistors with an Anodizing Electrode (in Czech)
Elektrotechnicky casopis, 26, 297-304 (1975) 
 27. J. Vacik, V. Kudela, J. Kopecek
Concentration Potentials of Hydrophilic Membranes Containing Ionogenic Groups
Europ. Polym. J., 11, 331-335 (1975) 
 26. Z. Voldrich, Z. Tomanek, J. Vacik, J. Kopecek
Long-Term Experience with the Poly(Glycol Monomethacrylate) Gel in Plastic Operations of the Nose
J. Biomed. Mater. Res., 9, 675-685 (1975) 
 25. J. Kolarik, J. Vacik, J. Kopecek
Relaxation Behaviour of Poly(2-Hydroxyethyl Acrylate) and its Copolymers with 2-Hydroxyethyl Methacrylate
Intern. J. Polym. Mater., 3, 259-268 (1975) 
 24. L. Sprincl, J. Kalal, J. Kopecek
Evaluation of Biological Properties of Polymeric Materials (in Czech)
Lekar a technika, 6, 110-114 (1974) 
 23. J. Kopecek, H. Bazilova
Poly[N-(2-Hydroxypropyl)methacrylamide]. III. Crosslinking Copolymerization
Europ. Polym. J., 10, 465-470 (1974) 
 22. M. Bohdanecky, H. Bazilova, J. Kopecek
Poly[N-(2-Hydroxypropyl)methacrylamide]. II. Hydrodynamic Properties of Diluted Polymer Solutions
Europ. Polym. J., 10, 405-410 (1974) 
 21. J. Kopecek, L. Sprincl
Relationship Between the Structure and Biocompatibility of Hydrophilic Gels
Polymers in Medicine (Wroclaw), 4, 109-117 (1974)
 20.  K. Ulbrich, L. Sprincl, J. Kopecek
Biocompatibility of Poly(2,4-Pentadiene-1-ol)
J. Biomed. Mater. Res., 8, 155-161 (1974)
 19.  J. Kopecek, H. Bazilova
Poly[N-(2-Hydroxypropyl)methacrylamide]. 1. Radical Polymerization and Copolymerization
Europ. Polym. J., 9, 7-14 (1973)
 18.  L. Sprincl, J. Kopecek, D. Lim
Effect of the Structure of Poly(Glycol Monomethacrylate) Gels on the Calcification of Implants
Calc. Tiss. Res., 13, 63-72 (1973)
 17.  J. Kopecek, L. Sprincl, D. Lim
New Types of Synthetic Infusion Solutions. I. Investigation of the Effect of Solutions of Some Hydrophilic Polymers on Blood
J. Biomed. Mater. Res., 7, 179-191 (1973)
 16.  J. Kopecek, J. Vacik
Effect of Hydrophilic Character of the Polymeric Backbone on Membrane Permeability
Collection Czechoslov. Chem. Commun., 38, 854-860 (1973)
 15.  J. Kopecek, L. Sprincl, H. Bazilova, J. Vacik
Biological Tolerance of Poly(N-Substituted Acrylamides)
J. Biomed. Mater. Res., 7, 111-121 (1973)
 14.  L. Sprincl, J. Vacik, J. Kopecek
Biological Tolerance of Ionogenic Hydrophilic Gels
J. Biomed. Mater. Res., 7, 123-136 (1973)
 13.  J. Kopecek, D. Lim
Mechanism of Three-Dimensional Polymerization of Glycol Methacrylates. IV. The System Triglycol Monomethacrylate - Glycol Dimethacrylates - Water
Collection Czechoslov. Chem. Commun., 36, 3394-3398 (1971)
 12. J. Kopecek, D. Lim
Mechanism of Three-Dimensional Polymerization of Glycol Methacrylates III. Contribution to the Polymerization Kinetics of the System Diglycol Monomethacrylate - Glycol Dimethacrylates - Water
Collection Czechoslov. Chem. Commun., 36, 2703-2707 (1971)
 11. L. Sprincl, J. Kopecek, D. Lim
Effect of Porosity of Heterogeneous Poly(Glycol Monomethacrylate) Gels on the Healing-in of Test Implants
J. Biomed. Mater. Res., 5, 447-458 (1971)
 10. J. Kopecek, J. Vacik, D. Lim
Permeability of Membranes Containing Ionogenic Groups
J. Polym. Sci. A-1, 9, 2801-2815 (1971)
 9. J. Kopecek, D. Lim
Mechanism of Three-Dimensional Polymerization of Glycol Methacrylates. II. The System Glycol Monomethacrylate - Glycol Dimethacrylates - Solvents
J. Polym. Sci. A-1, 9, 147-154 (1971)
 8. L. Sprincl, J. Vacik, J. Kopecek, D. Lim
Biological Tolerance of Poly(N-Substituted Methacrylamides)
J. Biomed. Mater. Res., 5, 197-205 (1971)
 7. J. Kopecek, S. Sourirajan
Performance of Porous Cellulose Acetate Membranes for the Reverse Osmosis Separation of Organic Liquids
Ind. Eng. Chem. Process Design Develop., 9, 5-12 (1970)
 6. J. Kopecek
Reverse Osmosis (in Czech)
Chem. listy, 63, 1338-1353 (1969)
 5. J. Kopecek, S. Sourirajan
Equisorptic Composition in Reverse Osmosis
Can. J. Chem., 47, 3467-3469 (1969)
 4. J. Kopecek, S. Sourirajan
Performance of Porous Cellulose Acetate Membranes in Some Reverse Osmosis Experiments
Ind. Eng. Chem. Prod. Res. Develop., 8, 274-279 (1969)
 3. J. Kopecek, S. Sourirajan
Structure of Porous Cellulose Acetate Membranes and a Method for Improving Their Performance in Reverse Osmosis
J. Appl. Polym. Sci., 13, 637-657 (1969)
 2. J. Jokl, J. Kopecek, D. Lim
Mechanism of Three-Dimensional Polymerization of the System Methyl Methacrylate - Glycol Dimethacrylate. Determination of the Structure of the Three-Dimensional Product
J. Polym. Sci. A-1, 6, 3041-3048 (1968)
 1. J. Kopecek, J. Jokl, D. Lim
Mechanism of Three-Dimensional Polymerization of Glycol Methacrylates (in German)
J. Polym. Sci., C 16, 3877-3889 (1968)

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